• Login
    View Item 
    •   UMB Digital Archive
    • UMB Open Access Articles
    • UMB Open Access Articles
    • View Item
    •   UMB Digital Archive
    • UMB Open Access Articles
    • UMB Open Access Articles
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UMB Digital ArchiveCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    Display statistics

    Current Strategies and Potential Prospects of Nanomedicine-Mediated Therapy in Inflammatory Bowel Disease

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Author
    Chen, Fengqian
    Liu, Qi
    Xiong, Yang
    Xu, Li
    Date
    2021-06-23
    Journal
    International Journal of Nanomedicine
    Publisher
    Dove Press
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.2147/IJN.S310952
    http://www.ncbi.nlm.nih.gov/pmc/articles/pmc8236271/
    Abstract
    Inflammatory bowel diseases (IBD) such as Crohn's disease and ulcerative colitis are highly debilitating. IBDs are associated with the imbalance of inflammatory mediators within the inflamed bowel. Conventional drugs for IBD treatment include anti-inflammatory medications and immune suppressants. However, they suffer from a lack of bioavailability and high dose-induced systemic side effects. Nanoparticle (NP)-derived therapy improves therapeutic efficacy and increases targeting specificity. Recent studies have shown that nanomedicines, based on bowel disease's pathophysiology, are a fast-growing field. NPs can prolong the circulation period and reduce side effects by improving drug encapsulation and targeted delivery. Here, this review summarizes various IBD therapies with a focus on NP-derived applications, whereas their challenges and future perspectives have also been discussed.
    Rights/Terms
    © 2021 Chen et al.
    Keyword
    inflammatory bowel disease
    nanomedicine applications
    nanoparticles
    targeted delivery
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/16125
    ae974a485f413a2113503eed53cd6c53
    10.2147/IJN.S310952
    Scopus Count
    Collections
    UMB Open Access Articles

    entitlement

    Related articles

    • Nanoparticle-Mediated Drug Delivery Systems For The Treatment Of IBD: Current Perspectives.
    • Authors: Yang C, Merlin D
    • Issue date: 2019
    • The future of nanomedicine in optimising the treatment of inflammatory bowel disease.
    • Authors: Mohan LJ, Daly JS, Ryan BM, Ramtoola Z
    • Issue date: 2019 Jan
    • Nanomedicine and drug delivery strategies for treatment of inflammatory bowel disease.
    • Authors: Takedatsu H, Mitsuyama K, Torimura T
    • Issue date: 2015 Oct 28
    • Nanoparticles for oral delivery: targeted therapy for inflammatory bowel disease.
    • Authors: Li DF, Yang MF, Xu HM, Zhu MZ, Zhang Y, Tian CM, Nie YQ, Wang JY, Liang YJ, Yao J, Wang LS
    • Issue date: 2022 Aug 10
    • Application of Polymeric Nano-Materials in Management of Inflammatory Bowel Disease.
    • Authors: Minakshi P, Kumar R, Ghosh M, Brar B, Barnela M, Lakhani P
    • Issue date: 2020
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Policies | Contact Us | UMB Health Sciences & Human Services Library
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.