• Login
    View Item 
    •   UMB Digital Archive
    • School of Nursing
    • Doctor of Nursing Practice (DNP) Projects
    • View Item
    •   UMB Digital Archive
    • School of Nursing
    • Doctor of Nursing Practice (DNP) Projects
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UMB Digital ArchiveCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    Display statistics

    Clinical Practice Guideline on Utilizing Low-dose Ketamine Infusions for Treatment Resistant Depression

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Hunt_UtilizingLow-doseKetamine ...
    Size:
    855.5Kb
    Format:
    PDF
    Download
    Author
    Hunt, John H.
    Advisor
    Amos, Veronica Y.
    Date
    2021-05
    Type
    DNP Project
    
    Metadata
    Show full item record
    Other Titles
    Low-Dose Ketamine Infusion
    Abstract
    Problem & Purpose: Standardly prescribed medications have increasingly become less effective in mitigating depression. This finding has led practitioners to explore alternative ways to treat refractory depression. Ketamine, a dissociative anesthetic, given as a low-dose infusion has become an efficacious regiment for managing the treatment resistant populations symptomology. Clinicians at an outpatient infusion center observed an increase in infusion related hemodynamic abnormalities due to non-standardized infusion therapies. The development and implementation of an evidence-based clinical practice guideline to standardize the administration of low-dose ketamine infusions aims to help alleviate the identified institutional problem. Methods: An extensive literature review was conducted to evaluate the most current evidence regarding ideal ketamine infusion rates to manage treatment resistant depression. A draft clinical practice guideline was developed with assistance from the institution’s stakeholders. The Appraisal of Guidelines for Research and Evaluation II tool was utilized by the stakeholders to appraise the draft guidelines quality. The finalized guideline was presented to the anesthesia team members and critique via provider feedback questionnaire was elicited. Results: The appraisal tools overall domain rating was an 88.9%, which represented a high-quality practice guideline. Provider feedback questionnaire results showed the developed guideline was accepted by stakeholders and anesthesia staff. Implementation of the new practice guideline was recommended without any changes. Conclusion: The anesthesia team valued the developed guideline which led to its acceptance. However, sustainability will rely on the provider success rates based on the utilization of the guidelines recommended dose range as well as periodically collecting and assessing provider feedback questionnaire data to ascertain the level of continued staff buy-in.
    Keyword
    Depressive Disorder, Treatment Resistent--drug therapy
    Ketamine--therapeutic use
    Quality Improvement
    Practice Guideline
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/15744
    Collections
    Doctor of Nursing Practice (DNP) Projects

    entitlement

     
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Policies | Contact Us | UMB Health Sciences & Human Services Library
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.