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    Photodynamic Therapy for Biomodulation and Disinfection in Implant Dentistry: Is It Feasible and Effective?

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    Author
    Choe, Robert
    Balhaddad, Abdulrahman A
    Fisher, John P
    Melo, Mary Anne S
    Huang, Huang-Chiao
    Date
    2021-04-19
    Journal
    Photochemistry and Photobiology
    Publisher
    Blackwell Publishing
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1111/php.13434
    Abstract
    Dental implants are the most common rehabilitation and restorative treatment used to replace missing teeth. Biofilms adhere to implant surfaces to trigger implant-associated infection and inflammatory response. Clinically, the biofilm induces a local host response with the infiltration of phagocytic immune cells. The pro-inflammatory surroundings set off osteoclastogenesis, which leads to the septic loosening of the implant. The standard of dental care for implant-associated infection relies on a combination of surgery and antimicrobial therapy. Antimicrobial photodynamic therapy is a noninvasive and photochemistry-based approach capable of reducing bacterial load and modulating inflammatory responses. In this review, we explore the photobiomodulation and disinfection outcomes promoted by photodynamic therapy for implant infections, highlighting the quality of evidence on the most up-to-date studies, and discuss the major challenges on the advance of these therapeutic strategies. © 2021 American Society for Photobiology
    Rights/Terms
    © 2021 American Society for Photobiology.
    Keyword
    Photochemotherapy
    Dental Implants
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/15644
    ae974a485f413a2113503eed53cd6c53
    10.1111/php.13434
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