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dc.contributor.authorZella, Davide
dc.contributor.authorGiovanetti, Marta
dc.contributor.authorCella, Eleonora
dc.contributor.authorBorsetti, Alessandra
dc.contributor.authorCiotti, Marco
dc.contributor.authorCeccarelli, Giancarlo
dc.contributor.authorD'Ettorre, Gabriella
dc.contributor.authorPezzuto, Aldo
dc.contributor.authorTambone, Vittoradolfo
dc.contributor.authorCampanozzi, Laura
dc.contributor.authorMagheri, Marco
dc.contributor.authorUnali, Francesco
dc.contributor.authorBianchi, Martina
dc.contributor.authorBenedetti, Francesca
dc.contributor.authorPascarella, Stefano
dc.contributor.authorAngeletti, Silvia
dc.contributor.authorCiccozzi, Massimo
dc.date.accessioned2021-05-07T16:42:15Z
dc.date.available2021-05-07T16:42:15Z
dc.date.issued2021-04-28
dc.identifier.urihttp://hdl.handle.net/10713/15601
dc.description.abstractIntroduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has pushed the scientific community to undertake intense research efforts. Understanding SARS-CoV-2 biology is necessary to discover therapeutic or preventive strategies capable of containing the pandemic. Knowledge of the structural characteristics of the virus genome and proteins is essential to find targets for therapies and immunological interventions.Areas covered: This review covers different areas of expertise, genomic analysis of circulating strains, structural biology, viral mutations, molecular diagnostics, disease, and vaccines. In particular, the review is focused on the molecular approaches and modern clinical strategies used in these fields.Expert opinion: Molecular approaches to SARS-CoV-2 pandemic have been critical to shorten time for new diagnostic, therapeutic and prevention strategies. In this perspective, the entire scientific community is moving in the same direction. Vaccines, together with the development of new drugs to treat the disease, represent the most important strategy to protect human from viral disease and prevent further spread. In this regard, new molecular technologies have been successfully implemented. The use of a novel strategy of communication is suggested for a better diffusion to the broader public of new data and results.en_US
dc.description.urihttps://doi.org/10.1080/14737159.2021.1917998en_US
dc.description.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8095159/en_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Inc.en_US
dc.relation.ispartofExpert Review of Molecular Diagnosticsen_US
dc.subjectSARS-CoV-2en_US
dc.subjectdiagnosisen_US
dc.subjectmolecular epidemiologyen_US
dc.subjectpandemicen_US
dc.subjectvaccineen_US
dc.titleThe importance of genomic analysis in cracking the coronavirus pandemicen_US
dc.typeArticleen_US
dc.identifier.doi10.1080/14737159.2021.1917998
dc.identifier.pmid33849359
dc.source.beginpage1
dc.source.endpage16
dc.source.countryEngland


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