Ischemia-reperfusion Injury in the Transplanted Lung: A Literature Review
Prasad, Nikhil K
Kaczorowski, David J
Lau, Christine L
PublisherWolters Kluwer Health
MetadataShow full item record
AbstractLung ischemia-reperfusion injury (LIRI) and primary graft dysfunction are leading causes of morbidity and mortality among lung transplant recipients. Although extensive research endeavors have been undertaken, few preventative and therapeutic treatments have emerged for clinical use. Novel strategies are still needed to improve outcomes after lung transplantation. In this review, we discuss the underlying mechanisms of transplanted LIRI, potential modifiable targets, current practices, and areas of ongoing investigation to reduce LIRI and primary graft dysfunction in lung transplant recipients. © 2021 Lippincott Williams and Wilkins. All rights reserved.
Rights/TermsCopyright © 2020 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.
Identifier to cite or link to this itemhttp://hdl.handle.net/10713/15518
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