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AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to nearly every corner of the globe, causing societal instability. The resultant coronavirus disease 2019 (COVID-19) leads to fever, sore throat, cough, chest and muscle pain, dyspnoea, confusion, anosmia, ageusia and headache. These can progress to life-threatening respiratory insufficiency, also affecting the heart, kidney, liver and nervous systems. The diagnosis of SARS-CoV-2 infection is often confused with that of influenza and seasonal upper respiratory tract viral infections. Due to available treatment strategies and required containments, rapid diagnosis is mandated. This Review brings clarity to the rapidly growing body of available and in-development diagnostic tests, including nanomaterial-based tools. It serves as a resource guide for scientists, physicians, students and the public at large. Copyright 2021, Springer Nature Limited.
SponsorsWe thank D. Meigs, University of Nebraska Medical Center, for proofreading and providing feedback on the manuscript. This work was supported by the National Institutes of Health R01 MH121402-01A1, R01 MH121402P01, R01 AG043540, R01 AG043530, P01 DA028555, P30 MH062261, R01 MH115860, R01 NS034249, R01 NS036126, the Carol Swartz Emerging Neuroscience Fund and the Margaret R. Larson Professorship. C.P. receives support from Cancer Australia (APP1145657) and the Garnett Passe and Rodney Williams Foundation.
Identifier to cite or link to this itemhttp://hdl.handle.net/10713/15351