Date
2021-02-17Journal
Frontiers in PharmacologyPublisher
Frontiers Media S.A.Type
Article
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Show full item recordAbstract
The interaction between drugs and various transporters is one of the decisive factors that affect the pharmacokinetics and pharmacodynamics of drugs. The organic cation transporter 1 (OCT1) is a member of the Solute Carrier 22A (SLC22A) family that plays a vital role in the membrane transport of organic cations including endogenous substances and xenobiotics. This article mainly discusses the drug-drug interactions (DDIs) mediated by OCT1 and their clinical significance.Rights/Terms
Copyright © 2021 Zhou, Zeng and Shu.Identifier to cite or link to this item
http://hdl.handle.net/10713/14974ae974a485f413a2113503eed53cd6c53
10.3389/fphar.2021.628705
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