JournalTremor and Other Hyperkinetic Movements (New York, N.Y.)
MetadataShow full item record
AbstractBackground: Reports of drummers’ dystonia are rare, particularly compared to the literature on dystonia in string, piano and brass players. Several cases of drummers’ dystonia have been included in large series of multiple instrumentalists, but there are few reports comprised exclusively of drummers with musicians’ dystonia. We present here a series of 12 drummers with task-specific, focal dystonia affecting their upper limbs while drumming and spanning multiple playing techniques and musical styles. Methods: We conducted a retrospective chart review of drummers with dystonia seen at academic Movement Disorders centers. Results: All 12 patients were male, and the majority eventually developed spread of dystonia to tasks other than drumming. Ten of the 12 had dystonia affecting their fingers, while 8/12 had dystonia affecting the wrist. Only 1/12 had involvement proximal to the wrist. Pharmacologic interventions were largely ineffective; 3 had some benefit from botulinum toxin injections, but this was limited by problematic weakness in one drummer. Discussion: The phenomenology in our series is concordant with prior reported cases, demonstrating frequent wrist involvement, though we also found that a greater proportion of patients had dystonia affecting the fingers. It could be hypothesized that different drumming techniques or musical styles modulate the relative risk of dystonic involvement of the different anatomical regions of the upper limb. Highlights: Drummers’ dystonia is one of the least common forms of musicians’ dystonia, though this may reflect fewer numbers of these instrumentalists. We present the largest series of drummers’ dystonia and review previously published cases. Our cohort, representing diverse drumming styles, showed frequent involvement of dystonia in the wrists and fingers. © 2021 The Author(s).
Rights/TermsCopyright: © 2021 The Author(s).
focal hand dystonia
task specific dystonia
Identifier to cite or link to this itemhttp://hdl.handle.net/10713/14961
- Dystonia in Performing Artists: Beyond Focal Hand Dystonia.
- Authors: Ray S, Pal PK
- Issue date: 2021 Mar 9
- Expertise-Related Differences in Wrist Muscle Co-contraction in Drummers.
- Authors: Beveridge S, Herff SA, Buck B, Madden GB, Jabusch HC
- Issue date: 2020
- Assessment of the effects of Kinesiotaping on musical motor performance in musicians suffering from focal hand dystonia: a pilot study.
- Authors: Bravi R, Ioannou CI, Minciacchi D, Altenmüller E
- Issue date: 2019 Oct
- Exercise-related cognitive effects on sensory-motor control in athletes and drummers compared to non-athletes and other musicians.
- Authors: Bianco V, Berchicci M, Perri RL, Quinzi F, Di Russo F
- Issue date: 2017 Sep 30
- Effects of stick use on bimanual coordination performance during rapid alternate tapping in drummers.
- Authors: Fujii S, Oda S
- Issue date: 2009 Jul
Showing items related by title, author, creator and subject.
Status Dystonicus, Oculogyric Crisis and Paroxysmal Dyskinesia in a 25 Year-Old Woman with a Novel Variant, K457E.Buckley, Cliona; Williams, Jennifer; Munteanu, Tudor; King, Mary; Park, Su Mi; Meredith, Andrea L; Lynch, Timothy (Center for Digital Research and Scholarship, 2020-10-27)The diagnosis of a paroxysmal dyskinesia is difficult and status dystonicus is a rare life threatening movement disorder characterised by severe, frequent or continuous episodes of dystonic spasms. A 25 year old woman with chronic ataxia and paroxysmal dyskinesia presented with facial twitching, writhing of arms, oculogyric crisis and visual and auditory hallucinations. She developed respiratory failure and was ventilated. No cause was found so whole exome sequencing was performed and this revealed a novel, non-synonymous heterozygous variant in exon 11 of the KCNMA1 gene, K457E (c 1369A>G) in the patient but not her parents. This variant has not been previously reported in gnomAD or ClinVar. The finding of a de novo variant in a potassium channel gene guided a trial of the potassium channel antagonist 3,4 diaminopyridine resulting in significant improvement, discharge from the intensive care unit and ultimately home.
Risk of spread in adult-onset isolated focal dystonia: A prospective international cohort studyBerman, B.D.; Groth, C.L.; Reich, S.G. (BMJ Publishing Group, 2019)Objective: Isolated focal dystonia can spread to muscles beyond the initially affected body region, but risk of spread has not been evaluated in a prospective manner. Furthermore, body regions at risk for spread and the clinical factors associated with spread risk are not well characterised. We sought here to prospectively characterise risk of spread in recently diagnosed adult-onset isolated focal dystonia patients. Methods: Patients enrolled in the Dystonia Coalition with isolated dystonia affecting only the neck, upper face, hand or larynx at onset of symptoms were included. Timing of follow-up visits was based on a sliding scale depending on symptom onset and ranged from 1 to 4 years. Descriptive statistics, Kaplan-Meier survival curves and Cox proportional hazard regression models were used to assess clinical characteristics associated with dystonia spread. Results: 487 enrolled participants (68.3% women; mean age: 55.6±12.2 years) met our inclusion/exclusion criteria. Spread was observed in 50% of blepharospasm, 8% of cervical dystonia, 17% of hand dystonia and 16% of laryngeal dystonia cases. Most common regions for first spread were the oromandibular region (42.2%) and neck (22.4%) for blepharospasm, hand (3.5%) for cervical dystonia and neck for hand (12.8%) and laryngeal (15.8%) dystonia. Increased spread risk was associated with a positive family history (HR=2.18, p=0.012) and self-reported alcohol responsiveness (HR=2.59, p=0.009). Conclusions: Initial body region affected in isolated focal dystonia has differential risk and patterns of spread. Genetic factors likely influence the risk of spread. These findings can aid clinical prognostication and inform future investigations into potential disease-modifying treatments. Copyright Author(s).
Non-motor phenotypic subgroups in adult-onset idiopathic, isolated, focal cervical dystoniaWadon, Megan E; Bailey, Grace A; Yilmaz, Zehra; Hubbard, Emily; AlSaeed, Meshari; Robinson, Amy; McLauchlan, Duncan; Barbano, Richard L; Marsh, Laura; Factor, Stewart A; et al. (Wiley-Blackwell, 2021-07-21)Background: Non-motor symptoms are well established phenotypic components of adult-onset idiopathic, isolated, focal cervical dystonia (AOIFCD). However, improved understanding of their clinical heterogeneity is needed to better target therapeutic intervention. Here, we examine non-motor phenotypic features to identify possible AOIFCD subgroups. Methods: Participants diagnosed with AOIFCD were recruited via specialist neurology clinics (dystonia wales: n = 114, dystonia coalition: n = 183). Non-motor assessment included psychiatric symptoms, pain, sleep disturbance, and quality of life, assessed using self-completed questionnaires or face-to-face assessment. Both cohorts were analyzed independently using Cluster, and Bayesian multiple mixed model phenotype analyses to investigate the relationship between non-motor symptoms and determine evidence of phenotypic subgroups. Results: Independent cluster analysis of the two cohorts suggests two predominant phenotypic subgroups, one consisting of approximately a third of participants in both cohorts, experiencing increased levels of depression, anxiety, sleep impairment, and pain catastrophizing, as well as, decreased quality of life. The Bayesian approach reinforced this with the primary axis, which explained the majority of the variance, in each cohort being associated with psychiatric symptomology, and also sleep impairment and pain catastrophizing in the Dystonia Wales cohort. Conclusions: Non-motor symptoms accompanying AOIFCD parse into two predominant phenotypic sub-groups, with differences in psychiatric symptoms, pain catastrophizing, sleep quality, and quality of life. Improved understanding of these symptom groups will enable better targeted pathophysiological investigation and future therapeutic intervention.