Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome
Author
Giannitsis, EvangelosBlankenberg, Stefan
Christenson, Robert H
Frey, Norbert
von Haehling, Stephan
Hamm, Christian W
Inoue, Kenji
Katus, Hugo A
Lee, Chien-Chang
McCord, James
Möckel, Martin
Chieh, Jack Tan Wei
Tubaro, Marco
Wollert, Kai C
Huber, Kurt
Date
2021-02-26Journal
Clinical Research in Cardiology : official Journal of the German Cardiac SocietyPublisher
Springer Science and Business Media Deutschland GmbHType
Article
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Multiple new recommendations have been introduced in the 2020 ESC guidelines for the management of acute coronary syndromes with a focus on diagnosis, prognosis, and management of patients presenting without persistent ST-segment elevation. Most recommendations are supported by high-quality scientific evidence. The guidelines provide solutions to overcome obstacles presumed to complicate a convenient interpretation of troponin results such as age-, or sex-specific cutoffs, and to give practical advice to overcome delays of laboratory reporting. However, in some areas, scientific support is less well documented or even missing, and other areas are covered rather by expert opinion or subjective recommendations. We aim to provide a critical appraisal on several recommendations, mainly related to the diagnostic and prognostic assessment, highlighting the discrepancies between Guideline recommendations and the existing scientific evidence. © 2021, The Author(s).Keyword
Acute coronary syndromesCritical appraisal
Diagnosis
Guidelines
High-sensitivity troponin
Management
Non-ST-segment elevation
Prognosis
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http://hdl.handle.net/10713/14959ae974a485f413a2113503eed53cd6c53
10.1007/s00392-021-01821-2
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