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    Critical appraisal of the 2020 ESC guideline recommendations on diagnosis and risk assessment in patients with suspected non-ST-segment elevation acute coronary syndrome

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    Author
    Giannitsis, Evangelos
    Blankenberg, Stefan
    Christenson, Robert H
    Frey, Norbert
    von Haehling, Stephan
    Hamm, Christian W
    Inoue, Kenji
    Katus, Hugo A
    Lee, Chien-Chang
    McCord, James
    Möckel, Martin
    Chieh, Jack Tan Wei
    Tubaro, Marco
    Wollert, Kai C
    Huber, Kurt
    Show allShow less

    Date
    2021-02-26
    Journal
    Clinical Research in Cardiology : official Journal of the German Cardiac Society
    Publisher
    Springer Science and Business Media Deutschland GmbH
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1007/s00392-021-01821-2
    Abstract
    Multiple new recommendations have been introduced in the 2020 ESC guidelines for the management of acute coronary syndromes with a focus on diagnosis, prognosis, and management of patients presenting without persistent ST-segment elevation. Most recommendations are supported by high-quality scientific evidence. The guidelines provide solutions to overcome obstacles presumed to complicate a convenient interpretation of troponin results such as age-, or sex-specific cutoffs, and to give practical advice to overcome delays of laboratory reporting. However, in some areas, scientific support is less well documented or even missing, and other areas are covered rather by expert opinion or subjective recommendations. We aim to provide a critical appraisal on several recommendations, mainly related to the diagnostic and prognostic assessment, highlighting the discrepancies between Guideline recommendations and the existing scientific evidence. © 2021, The Author(s).
    Keyword
    Acute coronary syndromes
    Critical appraisal
    Diagnosis
    Guidelines
    High-sensitivity troponin
    Management
    Non-ST-segment elevation
    Prognosis
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/14959
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00392-021-01821-2
    Scopus Count
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