Development and deployment of COVID-19 vaccines for those most vulnerable
Author
Koff, Wayne CSchenkelberg, Theodore
Williams, Tere
Baric, Ralph S
McDermott, Adrian
Cameron, Cheryl M
Cameron, Mark J
Friemann, Matthew B
Neumann, Gabriele
Kawaoka, Yoshihiro
Kelvin, Alyson A
Ross, Ted M
Schultz-Cherry, Stacey
Mastro, Timothy D
Priddy, Frances H
Moore, Kristine A
Ostrowsky, Julia T
Osterholm, Michael T
Goudsmit, Jaap
Date
2021-02-03Journal
Science Translational MedicinePublisher
American Association for the Advancement of ScienceType
Article
Metadata
Show full item recordAbstract
Development of safe and effective COVID-19 vaccines is a global priority and the best hope for ending the COVID-19 pandemic. Remarkably, in less than 1 year, vaccines have been developed and shown to be efficacious and are already being deployed worldwide. Yet, many challenges remain. Immune senescence and comorbidities in aging populations and immune dysregulation in populations living in low-resource settings may impede vaccine effectiveness. Distribution of vaccines among these populations where vaccine access is historically low remains challenging. In this Review, we address these challenges and provide strategies for ensuring that vaccines are developed and deployed for those most vulnerable. Copyright © 2021 The Authors.Rights/Terms
Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.Identifier to cite or link to this item
http://hdl.handle.net/10713/14848ae974a485f413a2113503eed53cd6c53
10.1126/scitranslmed.abd1525
Scopus Count
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