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    Development and deployment of COVID-19 vaccines for those most vulnerable

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    Author
    Koff, Wayne C
    Schenkelberg, Theodore
    Williams, Tere
    Baric, Ralph S
    McDermott, Adrian
    Cameron, Cheryl M
    Cameron, Mark J
    Friemann, Matthew B
    Neumann, Gabriele
    Kawaoka, Yoshihiro
    Kelvin, Alyson A
    Ross, Ted M
    Schultz-Cherry, Stacey
    Mastro, Timothy D
    Priddy, Frances H
    Moore, Kristine A
    Ostrowsky, Julia T
    Osterholm, Michael T
    Goudsmit, Jaap
    Show allShow less

    Date
    2021-02-03
    Journal
    Science Translational Medicine
    Publisher
    American Association for the Advancement of Science
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1126/scitranslmed.abd1525
    Abstract
    Development of safe and effective COVID-19 vaccines is a global priority and the best hope for ending the COVID-19 pandemic. Remarkably, in less than 1 year, vaccines have been developed and shown to be efficacious and are already being deployed worldwide. Yet, many challenges remain. Immune senescence and comorbidities in aging populations and immune dysregulation in populations living in low-resource settings may impede vaccine effectiveness. Distribution of vaccines among these populations where vaccine access is historically low remains challenging. In this Review, we address these challenges and provide strategies for ensuring that vaccines are developed and deployed for those most vulnerable. Copyright © 2021 The Authors.
    Rights/Terms
    Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
    Keyword
    COVID-19 Vaccines--supply & distribution
    Vulnerable Populations
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/14848
    ae974a485f413a2113503eed53cd6c53
    10.1126/scitranslmed.abd1525
    Scopus Count
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    UMB Open Access Articles
    UMB Coronavirus Publications

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