The International Society for Minimally Invasive Cardiothoracic Surgery Expert Consensus Statement on Transcatheter and Surgical Aortic Valve Replacement in Low- and Intermediate-Risk Patients: A Meta-Analysis of Randomized and Propensity-Matched Studies.
Author
Thourani, Vinod HEdelman, J James
Holmes, Sari D
Nguyen, Tom C
Carroll, John
Mack, Michael J
Kapadia, Samir
Tang, Gilbert H L
Kodali, Susheel
Kaneko, Tsuyoshi
Meduri, Christopher U
Forcillo, Jessica
Ferdinand, Francis D
Fontana, Gregory
Suwalski, Piotr
Kiaii, Bob
Balkhy, Husam
Kempfert, Joerg
Cheung, Anson
Borger, Michael A
Reardon, Michael
Leon, Martin B
Popma, Jeffrey J
Ad, Niv
Date
2021-01-25Journal
Innovations (Philadelphia, Pa.)Publisher
SAGE Publications Inc.Type
Article
Metadata
Show full item recordAbstract
Early mortality was lower in TAVR compared to SAVR in RCTs, but not propensity-matched studies in low-risk cohorts (0.66% vs 1.5%; odds ratio [OR] = 0.44, 95% confidence interval [CI] 0.20 to 0.98, I2 = 0%). No difference in mortality between TAVR and SAVR was identified in intermediate-risk patients at early or later time points. Incidence of perioperative stroke in 3 low-risk RCTs was significantly lower in TAVR (0.4%) than SAVR (1.4%; OR = 0.33, 95% CI 0.13 to 0.81, I2 = 0%). There was no difference in stroke for intermediate-risk patients between TAVR and SAVR. The expert panel of cardiologists and cardiac surgeons provided recommendations for TAVR and SAVR in various clinical scenarios.Identifier to cite or link to this item
http://hdl.handle.net/10713/14696ae974a485f413a2113503eed53cd6c53
10.1177/1556984520978316
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