The International Society for Minimally Invasive Cardiothoracic Surgery Expert Consensus Statement on Transcatheter and Surgical Aortic Valve Replacement in Low- and Intermediate-Risk Patients: A Meta-Analysis of Randomized and Propensity-Matched Studies.
AuthorThourani, Vinod H
Edelman, J James
Holmes, Sari D
Nguyen, Tom C
Mack, Michael J
Tang, Gilbert H L
Meduri, Christopher U
Ferdinand, Francis D
Borger, Michael A
Leon, Martin B
Popma, Jeffrey J
JournalInnovations (Philadelphia, Pa.)
PublisherSAGE Publications Inc.
MetadataShow full item record
AbstractEarly mortality was lower in TAVR compared to SAVR in RCTs, but not propensity-matched studies in low-risk cohorts (0.66% vs 1.5%; odds ratio [OR] = 0.44, 95% confidence interval [CI] 0.20 to 0.98, I2 = 0%). No difference in mortality between TAVR and SAVR was identified in intermediate-risk patients at early or later time points. Incidence of perioperative stroke in 3 low-risk RCTs was significantly lower in TAVR (0.4%) than SAVR (1.4%; OR = 0.33, 95% CI 0.13 to 0.81, I2 = 0%). There was no difference in stroke for intermediate-risk patients between TAVR and SAVR. The expert panel of cardiologists and cardiac surgeons provided recommendations for TAVR and SAVR in various clinical scenarios.
Identifier to cite or link to this itemhttp://hdl.handle.net/10713/14696
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