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    Walk the Line-The Importance of Well-Informed Interpretation of QT Prolongation.

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    Author
    Noel, Zachary R
    See, Vincent Y
    Flannery, Alexander H
    Date
    2020-06-13
    Journal
    Annals of Pharmacotherapy
    Publisher
    SAGE Publications Inc.
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1177/1060028020934718
    Abstract
    Acute care pharmacists play an integral role in identifying drug-drug interactions that may predispose patients to QT prolongation. Although most pharmacists are equipped with a baseline understanding of drug interactions and the risks of QTc prolongation, few understand the limitations of QTc calculation and interpretation. In this commentary, we put forth the notion that at times health care providers, including pharmacists, place an overemphasis on the QTc interval. In the context of using the QTc to guide pharmacotherapy decisions, unintended consequences may include a cascade of effects leading to delays in treatment, suboptimal medication selection, alert fatigue, and overutilization of resources.
    Keyword
    QT interval
    arrhythmia
    drug-induced QT prolongation
    torsades de pointes
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/14233
    ae974a485f413a2113503eed53cd6c53
    10.1177/1060028020934718
    Scopus Count
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