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    First-Year Outcomes of Critical Congenital Heart Disease Screening in Maryland.

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    Author
    Badawi, Deborah
    Watson, Johnna
    Maschke, Steven
    Reid, Lawrence
    Date
    2019-08-18
    Journal
    Global Pediatric Health
    Publisher
    SAGE Publications Inc.
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1177/2333794X19868226
    Abstract
    Objectives. Newborn screening for critical congenital heart disease (CCHD) was added to the Recommended Uniform Screening Panel in 2011, and states have been gradually adding pulse oximetry as point-of-care screening to panels. Few data are available on the effectiveness of pulse oximetry as a mandated screening. This study describes outcomes of the first year of screening in Maryland. Methods. A web-based data collection tool for screening results and outcomes, eScreener Plus, was utilized. Data collected from the start of screening from September 1, 2012, to December 31, 2013, were analyzed. Well-baby nursery data were evaluated separately from neonatal intensive care unit (NICU) data to determine whether setting influenced effectiveness. Results. In the first 15 months of newborn screening for CCHD in Maryland, 4 asymptomatic infants were diagnosed with a critical cardiac condition by newborn screening. Eleven infants passed but were later identified with a primary or secondary target condition. Seventy-one percent of infants with CCHD were identified prenatally or by clinical signs and symptoms. Pulse oximetry screening for CCHD had a specificity of more than 99% in both the well-baby nursery and the NICU. Sensitivity in the well-baby nursery was 10% and 60% in the NICU. Conclusion. Further investigation and interpretation of specific protocols that were used and outcomes of screening is needed for continued refinement of the well-baby algorithm and NICU protocol development. Pulse oximetry screening in newborns provides valuable clinical information, but many infants with CCHD are still not identified with current protocols.
    Keyword
    Critical Congenital Heart Disease
    Newborn Screening
    Pulse Oximetry Screening
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/14220
    ae974a485f413a2113503eed53cd6c53
    10.1177/2333794X19868226
    Scopus Count
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    UMB Open Access Articles 2020

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