Risk factors for Toxoplasma gondii seropositivity in the Old Order Amish
AuthorMarkon, A O
Ryan, K A
Groer, M W
Daue, M L
Mitchell, B D
Postolache, T T
JournalEpidemiology and Infection
PublisherCambridge University Press
MetadataShow full item record
AbstractToxoplasma gondii is an important human disease-causing parasite. In the US, T. gondii infects >10% of the population, accrues economic losses of US$3.6 billion/year, and ranks as the second leading culprit of foodborne illness-related fatalities. We assessed toxoplasmosis risk among the Old Order Amish, a mostly homogenous population with high prevalence of T. gondii seropositivity, using a questionnaire focusing on food consumption/preparation behaviours and environmental risk factors. Analyses were conducted using multiple logistic regression. Consuming raw meat, rare meat, or unpasteurized cow or goat milk products were associated with increased odds of seropositivity [unadjusted ORs: 2.192, 1.613, 1.718, and 1.741, respectively). In separate models by sex, consuming raw meat, or consuming unpasteurized cow or goat milk products, were associated with increased odds of seropositivity among women; washing hands and touching meat with decreased odds of seropositivity among women [adjusted OR (AOR): 0.462]; and cleaning cat litterbox with increased odds of seropositivity among men (AOR: 5.241). This is the first study to assess associations between behavioural and environmental risk factors and T. gondii seropositivity in a US population with high seroprevalence for T. gondii. Our study emphasizes the importance of proper food safety behaviours to avoid risk of infection.
Identifier to cite or link to this itemhttp://hdl.handle.net/10713/14214
- <i>Toxoplasma gondii</i> Serointensity and Seropositivity: Heritability and Household-Related Associations in the Old Order Amish.
- Authors: Duffy AR, O'Connell JR, Pavlovich M, Ryan KA, Lowry CA, Daue M, Raheja UK, Brenner LA, Markon AO, Punzalan CM, Dagdag A, Hill DE, Pollin TI, Seyfang A, Groer MW, Mitchell BD, Postolache TT
- Issue date: 2019 Oct 3
- Positive association between <i>Toxoplasma gondii</i> IgG serointensity and current dysphoria/hopelessness scores in the Old Order Amish: a preliminary study.
- Authors: Wadhawan A, Dagdag A, Duffy A, Daue ML, Ryan KA, Brenner LA, Stiller JW, Pollin TI, Groer MW, Huang X, Lowry CA, Mitchell BD, Postolache TT
- Issue date: 2017
- Sleep onset insomnia, daytime sleepiness and sleep duration in relationship to <i>Toxoplasma gondii</i> IgG seropositivity and serointensity.
- Authors: Ahmad Z, Moustafa YW, Stiller JW, Pavlovich MA, Raheja UK, Gragnoli C, Snitker S, Nazem S, Dagdag A, Fang B, Fuchs D, Lowry CA, Postolache TT
- Issue date: 2017
- [Investigation of Toxoplasma gondii seropositivity in pregnant women attending the Antalya Training and Research Hospital for the last four years].
- Authors: Çekin Y, Kızılateş F, Gür N, Senol Y
- Issue date: 2011
- Toxoplasma gondii seroprevalence in pet cats in Norway and risk factors for seropositivity.
- Authors: Sævik BK, Krontveit RI, Eggen KP, Malmberg N, Thoresen SI, Prestrud KW
- Issue date: 2015 Dec