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    Evaluation of different ways to identify persistent positivity of lupus anticoagulant in systemic lupus erythematosus

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    Author
    Petri, Michelle A
    Avci, Mertcan
    Magder, Laurence S
    Date
    2020-11-02
    Journal
    Lupus Science & Medicine
    Publisher
    BMJ Publishing Group
    Type
    Article
    Other
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1136/lupus-2020-000406
    Abstract
    Among the 785 patients included in our analysis, the prevalence of persistent lupus anticoagulant as defined by the first two patient assessments was 4.3%. Annual assessment resulted in a prevalence of 6.6%, and using all 16 assessments resulted in a prevalence of 10.5%. The prevalence was substantially higher in men than in women, and in Caucasians than in African-Americans (p<0.01 for all comparisons). The rate of thrombosis was significantly elevated among those with persistently positive lupus anticoagulant by any definition (HR ranging from 2.75 to 3.42) relative to those without persistently positive lupus anticoagulant.
    Rights/Terms
    © Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
    Keyword
    antibodies
    antiphospholipid
    epidemiology
    lupus erythematosus
    systemic
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/14108
    ae974a485f413a2113503eed53cd6c53
    10.1136/lupus-2020-000406
    Scopus Count
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    UMB Open Access Articles 2020

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