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dc.contributor.authorGutierrez-Barbosa, Hernando
dc.contributor.authorMedina-Moreno, Sandra
dc.contributor.authorZapata, Juan C
dc.contributor.authorChua, Joel V
dc.date.accessioned2020-10-30T13:46:38Z
dc.date.available2020-10-30T13:46:38Z
dc.date.issued2020-10-03
dc.identifier.urihttp://hdl.handle.net/10713/13980
dc.description.abstractDengue is a major public health problem in hyperendemic countries like Colombia, the understanding of the epidemiological trends is important for the development of efficient public health policies. We conducted a systematic review of the epidemiologic data on dengue in Colombia from 1971 to 2020. A total of 375 relevant citations were identified, 36 of which fulfilled the inclusion criteria. The data of dengue and severe dengue cases, infection fatality rate, and serotype distribution were used to understand and identify gaps in the epidemiological knowledge in Colombia. The epidemiology of dengue in this country was characterized by five main outbreaks in 1998, 2002, 2010, 2013, and 2019 with high fatality rates in comparison with the average values reported in the Americas. The case fatality rate of severe dengue exceeded 2% and all four serotypes co-circulate throughout the country with some regional variations. Overall, the behavior of dengue in Colombia is influenced by multiple factors including seasonal temperature variation and socioeconomic conditions. Additionally, the most important barriers in the epidemiological surveillance of dengue may be due to the insufficient notification rate in some regions and the low active search for the circulation of different serotypes.en_US
dc.description.urihttps://doi.org/10.3390/tropicalmed5040156en_US
dc.language.isoenen_US
dc.publisherMDPI AGen_US
dc.relation.ispartofTropical Medicine and Infectious Diseaseen_US
dc.subjectColombiaen_US
dc.subjectdengue virusen_US
dc.subjectendemic diseasesen_US
dc.subjectepidemiologyen_US
dc.titleDengue Infections in Colombia: Epidemiological Trends of a Hyperendemic Countryen_US
dc.typeArticleen_US
dc.typeOtheren_US
dc.identifier.doi10.3390/tropicalmed5040156
dc.identifier.pmid33022908
dc.source.volume5
dc.source.issue4
dc.source.countrySwitzerland


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