Thromboembolic disease in COVID-19 patients: A brief narrative review.
Date
2020-09-14Journal
Journal of intensive carePublisher
Springer NatureType
ArticleOther
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Corona virus 2 (SARS-CoV2/ Severe Acute Respiratory Syndrome Corona Virus 2) infection has emerged as a global health crisis. Incidence of thromboembolic disease is reported to be high in SARS-CoV2 disease and is seen in a multitude of organ systems ranging from cutaneous thrombosis to pulmonary embolism, stroke or coronary thrombosis sometimes with catastrophic outcomes. Evidence points towards a key role of thromboembolism, hypercoagulability and over production of proinflammatory cytokines mimicking a "cytokine storm"which leads to multiorgan failure. This brief narrative review highlights the pathophysiology and risk factors of thromboembolic disease and provides a framework for management of anticoagulation based on the current evidence.Rights/Terms
© The Author(s) 2020.Identifier to cite or link to this item
http://hdl.handle.net/10713/13832ae974a485f413a2113503eed53cd6c53
10.1186/s40560-020-00483-y
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