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    Thromboembolic disease in COVID-19 patients: A brief narrative review.

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    Author
    Mondal, Samhati
    Quintili, Ashley L
    Karamchandani, Kunal
    Bose, Somnath
    Date
    2020-09-14
    Journal
    Journal of intensive care
    Publisher
    Springer Nature
    Type
    Article
    Other
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1186/s40560-020-00483-y
    Abstract
    Corona virus 2 (SARS-CoV2/ Severe Acute Respiratory Syndrome Corona Virus 2) infection has emerged as a global health crisis. Incidence of thromboembolic disease is reported to be high in SARS-CoV2 disease and is seen in a multitude of organ systems ranging from cutaneous thrombosis to pulmonary embolism, stroke or coronary thrombosis sometimes with catastrophic outcomes. Evidence points towards a key role of thromboembolism, hypercoagulability and over production of proinflammatory cytokines mimicking a "cytokine storm"which leads to multiorgan failure. This brief narrative review highlights the pathophysiology and risk factors of thromboembolic disease and provides a framework for management of anticoagulation based on the current evidence.
    Rights/Terms
    © The Author(s) 2020.
    Keyword
    COVID-19
    SARS-CoV2
    coagulation
    management
    thromboembolism
    thrombosis
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/13832
    ae974a485f413a2113503eed53cd6c53
    10.1186/s40560-020-00483-y
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