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    Human Typhi exposure generates differential multifunctional cross-reactive T-cell memory responses against Paratyphi and invasive nontyphoidal .

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    Author
    Rapaka, Rekha R
    Wahid, Rezwanul
    Fresnay, Stephanie
    Booth, Jayaum S
    Darton, Thomas C
    Jones, Claire
    Waddington, Claire S
    Levine, Myron M
    Pollard, Andrew J
    Sztein, Marcelo B
    Date
    2020-09-24
    Journal
    Clinical & translational immunology
    Publisher
    Wiley-Blackwell
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1002/cti2.1178
    Abstract
    There are no vaccines for most of the major invasive Salmonella strains causing severe infection in humans. We evaluated the specificity of adaptive T memory cell responses generated after Salmonella Typhi exposure in humans against other major invasive Salmonella strains sharing capacity for dissemination.
    Rights/Terms
    © 2020 The Authors. Clinical & Translational Immunology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc.
    Keyword
    Paratyphi
    S. Typhi
    T‐cell memory
    human challenge
    iNTS
    invasive Salmonella
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/13831
    ae974a485f413a2113503eed53cd6c53
    10.1002/cti2.1178
    Scopus Count
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