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    Toddler obesity prevention: A two-generation randomized attention-controlled trial

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    Author
    Black, Maureen M
    Hager, Erin R
    Wang, Yan
    Hurley, Kristen M
    Latta, Laura W
    Candelaria, Margo
    Caulfield, Laura E
    Date
    2020-09-04
    Journal
    Maternal & Child Nutrition
    Publisher
    Wolters Kluwer Health
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1111/mcn.13075
    Abstract
    Background. Donor-derived cell-free DNA (dd-cfDNA) is a noninvasive plasma biomarker to evaluate for transplant allograft rejection. The relationship between infectious complications in kidney allografts and dd-cfDNA has received cursory attention in prior publications. Methods. Retrospective review of all renal transplant recipients who underwent dd-cfDNA testing between November 2017 and August 2019. Results. We report on 7 cases in whom infections affecting the transplanted kidney were associated with elevation in dd-cfDNA without concomitant rejection or elevation in serum creatinine. Five patients had BK viremia, and 2 patients had urinary tract infection associated with elevated dd-cfDNA levels. Conclusions. These observations suggest that elevations in dd-cfDNA are not specific to kidney allograft rejection and can be associated with infections affecting the transplanted kidney. This biomarker may be valuable in evaluating infectious complications of kidney allografts.
    Rights/Terms
    © 2020 The Authors. Maternal & Child Nutrition published by John Wiley & Sons, Ltd.
    Keyword
    child feeding
    childhood obesity
    diet and physical activity intervention studies
    growth
    physical activity
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/13670
    ae974a485f413a2113503eed53cd6c53
    10.1111/mcn.13075
    Scopus Count
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    UMB Open Access Articles 2020

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