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dc.contributor.authorMerati, Arash
dc.date.accessioned2020-06-16T17:28:07Z
dc.date.available2020-06-16T17:28:07Z
dc.date.issued2020en_US
dc.identifier.urihttp://hdl.handle.net/10713/13072
dc.description2020
dc.descriptionBiomedical Sciences-Dental School
dc.descriptionUniversity of Maryland, Baltimore
dc.descriptionM.S.
dc.description.abstractControl of plaque biofilm is central to prevention of gingivitis. In addition to professional care, effective oral hygiene measures are known to improve gingival health. The objective of this study was to investigate the effect of chitosan/blackberry-extract, delivered in a chewing gum, as an adjunct to oral hygiene, on gingival inflammation and plaque biofilm accumulation. In this 12-week randomized controlled study, the use of chitosan/blackberry-extract gum was compared to placebo in 34 subjects (17/17). Plaque index(mPI) and gingival index(mGI) were the main outcome measures followed at baseline, week 2, 4, 8, and 12. Measured patient compliance and mPI had no significant difference between experimental and control at any interval during the study. mGI was significantly lower for the experimental group compared to control at 12 weeks(P<0.005). Chitosan/blackberry-extract chewing gum may be beneficial in reduction of clinical signs of gingival inflammation and has potential as an adjunct to routine oral hygiene.
dc.subjectfunctional chewing gumen_US
dc.subjectgingival inflammationen_US
dc.subject.meshChitosanen_US
dc.subject.meshDental Plaqueen_US
dc.subject.meshGingivitisen_US
dc.titleUse of a Functional Chewing Gum in Reduction of Gingival Inflammationen_US
dc.typedissertationen_US
dc.date.updated2020-06-04T16:03:23Z
dc.language.rfc3066en
dc.contributor.advisorShiau, Harlan
refterms.dateFOA2020-06-16T17:28:08Z


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