• Login
    View Item 
    •   UMB Digital Archive
    • School, Graduate
    • Theses and Dissertations All Schools
    • View Item
    •   UMB Digital Archive
    • School, Graduate
    • Theses and Dissertations All Schools
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UMB Digital ArchiveCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    Display statistics

    The Use of Naltrexone Among Young Adults with Opioid Use Disorder

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    Rozenberg_umaryland_0373D_11155.pdf
    Size:
    1.824Mb
    Format:
    PDF
    Download
    Author
    Rozenberg, Ilya
    Advisor
    Storr, Carla L.
    Date
    2020
    Type
    dissertation
    
    Metadata
    Show full item record
    Abstract
    Background: The rapid growth of opioid addiction carries catastrophic consequences for the young generation affecting families and society at large. To address problems of compliance and retention in treatment, new, innovative approaches synthesizing available interdisciplinary models with both medical and psychosocial approaches adapted to the user’s environment are necessary. Purpose: This dissertation explored the evidence in literature on the use of naltrexone (XR-NTX) in adolescents and young adults. It also examined relationships between retention in treatment and 1) family engagement, 2) assertive community outreach and 3) use of other substances in a sample of youth being treated for opioid use disorders (OUD). Methods: A scoping literature review provided a synthesis of the current state of evidence on safety and efficacy of XR-NTX use in treating youth with OUD and alcohol use disorders. Relationships between retention in treatment and family engagement, assertive outreach, and comorbid substance use were explored using data from a retrospective chart review of 41 young adults (16-26 years of age) who participated in a randomized open-label pilot study of OUD treatment at a community-based substance use disorder treatment program. Results: Family sessions contributed to increased retention in treatment, evidenced by the increase in number of injections. More frequent communication resulted in a higher number of received injections. There is a positive correlation between number of family sessions and number of doses. The total number of significant other contacts does not have a significant effect on the number of injections while the total number of patient contacts was significant. The study showed that most young adults seeking treatment for opioid use disorder are also using other substances and that the longer they stay in treatment, the greater the chance of decreasing use of other drugs. The review of 13 studies with 462 young adults found that Naltrexone is effective in improving treatment retention, extending abstinence, and preventing relapses in adolescents and young adults with OUD. Conclusion: Family support and ongoing communications could result in increasing retention in treatment. The study allowed for a better understanding of the relationship between treatment of opioid use and use of other substances.
    Description
    2020
    Nursing
    University of Maryland, Baltimore
    Ph.D.
    Keyword
    alcohol abuse
    community outreach
    opioid abuse
    Young adults
    Adolescent
    Alcohol-Related Disorders
    Naltrexone
    Opioid-Related Disorders
    Identifier to cite or link to this item
    http://hdl.handle.net/10713/13041
    Collections
    Theses and Dissertations School of Nursing
    Theses and Dissertations All Schools

    entitlement

     
    DSpace software (copyright © 2002 - 2023)  DuraSpace
    Quick Guide | Policies | Contact Us | UMB Health Sciences & Human Services Library
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.