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    The Overton Window and a Less Dogmatic Approach to Antibiotics

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    Author
    Morgan, D.J.
    Date
    2020
    Journal
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
    Publisher
    Oxford University Press
    Type
    Article
    
    Metadata
    Show full item record
    See at
    http://doi.org/10.1093/cid/ciz984
    Abstract
    This analysis summarizes a set of recent, innovative trials in infectious diseases that redefine previous, non-evidence based "rules" for antibiotics. Recent trials in infectious diseases have led to reconsidering the traditional treatment of infectious diseases by changing the duration or type of traditional antibiotics or evaluating new antibiotics for approval. These trials have used the noninferiority trial approach. The noninferiority trial design and recent infectious disease trials of relevance are discussed in this viewpoint. My objective was to analyze recent trials in infectious disease and consider needs for future trials.
    Keyword
    antibiotics
    antimicrobial stewardship
    bacteremia
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085535847&doi=10.1093%2fcid%2fciz984&partnerID=40&md5=75e7f25ab13325fb1b583e0d1d7f35d1; http://hdl.handle.net/10713/12987
    ae974a485f413a2113503eed53cd6c53
    10.1093/cid/ciz984
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    UMB Open Access Articles 2020

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