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    Effects of air pollution and other environmental exposures on estimates of severe influenza illness, Washington, USA

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    Author
    Somayaji, R.
    Neuzil, K.M.
    Ortiz, J.R.
    Date
    2020
    Journal
    Emerging Infectious Diseases
    Publisher
    Centers for Disease Control and Prevention (CDC)
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.3201/eid2605.190599
    Abstract
    Ecologic models of influenza burden may be confounded by other exposures that share winter seasonality. We evaluated the effects of air pollution and other environmental exposures in ecologic models estimating influenza-associated hospitalizations. We linked hospitalization data, viral surveillance, and environmental data, including temperature, relative humidity, dew point, and fine particulate matter for 3 counties in Washington, USA, for 2001-2012. We used negative binomial regression models to estimate the incidence of influenza-associated respiratory and circulatory (RC) hospitalizations and to assess the effect of adjusting for environmental exposures on RC hospitalization estimates. The modeled overall incidence rate of influenza-associated RC hospitalizations was 31/100,000 person-years. The environmental parameters were statistically associated with RC hospitalizations but did not appreciably affect the event rate estimates. Modeled influenza-associated RC hospitalization rates were similar to published estimates, and inclusion of environmental covariates in the model did not have a clinically important effect on severe influenza estimates.
    Sponsors
    This work was supported by the Robert Wood Johnson Harold Amos Medical Faculty Development Program (grant 67423 to J.R.O.; http://www.amfdp.org).
    Keyword
    Influenza, Human
    Air Pollution
    Environmental Exposure
    Washington
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083811842&doi=10.3201%2feid2605.190599&partnerID=40&md5=f03e550751953dafe938daae49cb28a5; http://hdl.handle.net/10713/12815
    ae974a485f413a2113503eed53cd6c53
    10.3201/eid2605.190599
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