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dc.contributor.authorReclusa, P.
dc.contributor.authorde Miguel-Pérez, D.
dc.contributor.authorRolfo, C.
dc.date.accessioned2020-05-01T19:06:52Z
dc.date.available2020-05-01T19:06:52Z
dc.date.issued2020
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85083631807&doi=10.1038%2fs41598-020-62920-0&partnerID=40&md5=950988b49295214878c27fc6e11593ff
dc.identifier.urihttp://hdl.handle.net/10713/12688
dc.description.abstractIn the last decade, extracellular vesicles (EVs) have become a hot topic. The findings on EVs content and effects have made them a major field of interest in cancer research. EVs, are able to be internalized through integrins expressed in parental cells, in a tissue specific manner, as a key step of cancer progression and pre-metastatic niche formation. However, this specificity might lead to new opportunities in cancer treatment by using EVs as devices for drug delivery. For future applications of EVs in cancer, improved protocols and methods for EVs isolation and visualization are required. Our group has put efforts on developing a protocol able to track the EVs for in vivo internalization analysis. We showed, for the first time, the videos of labeled EVs uptake by living lung cancer cells. Copyright 2020, The Author(s).en_US
dc.description.sponsorshipUniversidad de Granada, UGR 2018/19; Associazione Italiana per la Ricerca sul Cancro, AIRC AUHA.15.12en_US
dc.description.urihttps://doi.org/10.1038/s41598-020-62920-0en_US
dc.language.isoen_USen_US
dc.publisherNature Researchen_US
dc.relation.ispartofScientific Reports
dc.subjectin vivo internalization analysisen_US
dc.subject.lcshCancer--Researchen_US
dc.subject.lcshCancer--Treatmenten_US
dc.subject.meshExtracellular Vesiclesen_US
dc.subject.meshIntegrinsen_US
dc.titleImproving extracellular vesicles visualization: From static to motionen_US
dc.typeArticleen_US
dc.identifier.doi10.1038/s41598-020-62920-0
dc.identifier.pmid32300120


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