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dc.contributor.authorSilva, P.A.M.
dc.contributor.authorGarcia, I.M.
dc.contributor.authorMelo, M.A.
dc.date.accessioned2020-04-27T19:48:54Z
dc.date.available2020-04-27T19:48:54Z
dc.date.issued2020
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85083314967&doi=10.3390%2fjfb11010009&partnerID=40&md5=caa4c64aa17a8a778ba8faa38b5c26e8
dc.identifier.urihttp://hdl.handle.net/10713/12649
dc.description.abstractThis in vitro study evaluated the effect of myristyltrimethylammonium bromide (MYTAB) on the physical, chemical, and biological properties of an experimental dental resin. The resin was formulated with dental dimetacrylate monomers and a photoinitiator/co-initiator system. MYTAB was added at 0.5 (G0.5%), 1 (G1%), and 2 (G2%) wt %, and one group remained without MYTAB and was used as the control (GCtrl). The resins were analyzed for the polymerization kinetics, degree of conversion, ultimate tensile strength (UTS), antibacterial activity against Streptococcus mutans, and cytotoxicity against human keratinocytes. Changes in the polymerization kinetics profiling were observed, and the degree of conversion ranged from 57.36% (±2.50%) for G2% to 61.88% (±1.91%) for G0.5%, without a statistically significant difference among groups (p > 0.05). The UTS values ranged from 32.85 (±6.08) MPa for G0.5% to 35.12 (±5.74) MPa for GCtrl (p > 0.05). MYTAB groups showed antibacterial activity against biofilm formation from 0.5 wt % (p < 0.05) and against planktonic bacteria from 1 wt % (p < 0.05). The higher the MYTAB concentration, the higher the cytotoxic effect, without differences between GCtrl e G0.5% (p > 0.05). In conclusion, the addition of 0.5 wt % of MYTAB did not alter the physical and chemical properties of the dental resin and provided antibacterial activity without cytotoxic effect. Copyright 2020 by the authors.en_US
dc.description.sponsorshipThis study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior-Brasil (CAPES)-Finance Code 001.en_US
dc.description.urihttps://doi.org/10.3390/jfb11010009en_US
dc.language.isoen_USen_US
dc.publisherMDPI AGen_US
dc.relation.ispartofJournal of Functional Biomaterials
dc.subjectAnti-bacterial agentsen_US
dc.subjectBiocompatible materialsen_US
dc.subjectBiofilmsen_US
dc.subjectDental cariesen_US
dc.subjectDental materialsen_US
dc.subjectDentistryen_US
dc.subjectQuaternary ammonium compoundsen_US
dc.titleMyristyltrimethylammonium Bromide (MYTAB) as a cationic surface agent to inhibit Streptococcus mutans Grown over dental resins: An in vitro studyen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/jfb11010009


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