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    Attitudes and Perceptions Toward Authorized Deception: A Pilot Comparison of Healthy Controls and Fibromyalgia Patients

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    Author
    Goo, S.J.
    Frangos, E.
    Colloca, L.
    Date
    2020
    Journal
    Pain medicine (Malden, Mass.)
    Publisher
    Oxford University Press
    Type
    Article
    
    Metadata
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    See at
    https://doi.org/10.1093/pm/pnz081
    Abstract
    Objective: Little is known about the perceptions and attitudes of participants who volunteer in studies involving authorized deception. Thus, this cross-sectional pilot study measured, for the first time, the perceptions about participation in an authorized-deception placebo analgesia study in chronic pain patients with fibromyalgia and assessed whether their perceptions differed from healthy controls. Methods: An anonymous survey with questions about trust in research and willingness to participate in future research involving deception was mailed to participants in both groups after completion of the parent study. Statistical analyses were performed using the Mann-Whitney U and chi-square tests (31 controls and 16 fibromyalgia patients were included in the analyses). Results: The majority of participants expressed little or no concern about the deception, still trusted the scientific process, and found the debriefing procedure helpful and worthwhile. Group differences were found in willingness to 1) participate in the parent study had the deceptive element been disclosed in advance (controls = definitely, fibromyalgia patients = probably, U = 341.5, P = 0.01) and 2) participate in future studies (controls = definitely, fibromyalgia patients = probably, U = 373, P < 0.001). Conclusions: Despite slightly less favorable responses of fibromyalgia patients and the relatively small size of the study, these findings suggest that attitudes and perceptions about participating in an authorized placebo study remain positive in both healthy and chronic pain populations.
    Keyword
    Deception
    Pain
    Perception
    Placebo Analgesia
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85083003316&doi=10.1093%2fpm%2fpnz081&partnerID=40&md5=e3f7093a626c502c80c6241c960eda18; http://hdl.handle.net/10713/12610
    ae974a485f413a2113503eed53cd6c53
    10.1093/pm/pnz081
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    UMB Open Access Articles 2020

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