Browsing UMB Coronavirus Publications by Author "Murphy, Colin"
Blood usage at a large academic center in Maryland in relation to the COVID-19 pandemic in 2020Murphy, Colin; Fontaine, Magali; Luethy, Paul; McGann, Heather; Jackson, Bryon (Blackwell Publishing, 2021-04-20)Background: Blood usage and collections were impacted throughout 2020 both by the severity of the COVID-19 pandemic as well as public health decisions affecting hospital operations. We sought to understand the longer-term effects of the pandemic on blood usage via changes in case volume and clinical intensity as well as whether the blood needs of COVID-19-positive patients differed from other transfused patients. Study design and methods: A single-center retrospective study of blood use in 2020 as compared to 2014–2019 was conducted at a tertiary care center. Statistical analysis was performed in an R-based workflow. p values are reported using two-sided t-tests for total hospital blood usage and using Mann–Whitney U tests for comparisons of patient blood usage. Results: Mean monthly red cell usage in 2020 decreased by 11.2% (p =.003), plasma usage decreased by 23.8%, (p <.001) platelet usage decreased by 11.4% (p <.001), and monthly cryoprecipitate use increased by 18% (p =.03). A linear regression model predicted significant associations between total blood usage and the year, number of Medicare eligible discharges, and Case Mix Index. COVID-19-positive patients requiring at least one blood product did not use significantly different amounts of red cells, plasma, or platelets from all other transfused patients. Conclusions: Year 2020 began with decreased blood usage that was normalized by late spring. Reassuringly, transfused COVID-19-positive patients in general and those requiring ICU level care do not use significantly increased amounts of blood as compared to similar transfused hospital patients. © 2021 AABB
Tools for rapid analysis of blood usage and inventory during the COVID-19 pandemicMurphy, Colin; Jackson, Bryon; Fontaine, Magali (Wiley-Blackwell, 2020-08-10)Background The COVID‐19 pandemic caused downtrends in both blood collections and blood usage. Rapidly visualizing the impact of the pandemic and newly implemented hospital policies on usage could potentially inform blood ordering practices to help avoid wastage. Study Design and Methods Blood usage data were obtained from the laboratory information system. An R‐based workflow was written in R Markdown for analysis and visualization. Reports were generated daily and shared with blood bank leadership. Selected reports were shared with institutional leadership, other departments, and collaborating blood suppliers. Results Mean daily transfusions dropped 42% from 3/9‐13 to 3/16‐20, with a significant decrease in usage of red cells, plasma, and cryoprecipitate. The greatest decline in use was seen in the general operating rooms, whereas outpatient transfusions remained steady. Weekly total blood usage decreased through the end of March into April and returned to normal levels in May. Conclusion During two 5‐weekday periods of changing hospital policies, overall blood usage decreased by almost half. Visualization of usage by hospital location showed a large decrease in general operating room usage after cancellation of elective procedures. This data visualization has informed decisions to modify standing product orders during an initial period of decreased usage as well as return to normal orders in later months.