Browsing UMB Coronavirus Publications by Author "Dodd, Lori E"
Remdesivir for the Prevention of Invasive Mechanical Ventilation or Death in Coronavirus Disease 2019 (COVID-19): A Post Hoc Analysis of the Adaptive COVID-19 Treatment Trial-1 Cohort Data.Paules, Catharine I; Gallagher, Shannon K; Rapaka, Rekha R; Davey, Richard T; Doernberg, Sarah B; Grossberg, Robert; Hynes, Noreen A; Ponce, Philip O; Short, William R; Voell, Jocelyn; et al. (Oxford University Press, 2022-04-09)This post hoc analysis of the Adaptive Coronavirus Disease 2019 (COVID-19) Treatment Trial-1 (ACTT-1) shows a treatment effect of remdesivir (RDV) on progression to invasive mechanical ventilation (IMV) or death. Additionally, we create a risk profile that better predicts progression than baseline oxygen requirement alone. The highest risk group derives the greatest treatment effect from RDV.