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dc.contributor.authorvan, Tilburg, M.A.L.
dc.contributor.authorRunyan, D.K.
dc.contributor.authorZolotor, A.J.
dc.contributor.authorChristopher, Graham, J.
dc.contributor.authorDubowitz, H.
dc.contributor.authorLitrownik, A.J.
dc.contributor.authorChitkara, D.K.
dc.contributor.authorWhitehead, W.E.
dc.contributor.authorFlaherty, E.G.
dc.date.accessioned2020-02-07T21:22:38Z
dc.date.available2020-02-07T21:22:38Z
dc.date.issued2010
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-77949285109&doi=10.1370%2fafm.1053&partnerID=40&md5=17d7a596cd6c2947a77a95848bb874c6
dc.identifier.urihttp://hdl.handle.net/10713/11858
dc.description.abstractPurpose: Unexplained gastrointestinal symptoms are more common in adults who recall abuse as a child; however, data available on children are limited. The aim of this study was to investigate the association of childhood maltreatment and early development of gastrointestinal symptoms and whether this relation was mediated by psychological distress. Methods: Data were obtained from the Longitudinal Studies of Child Abuse and Neglect, a consortium of 5 prospective studies of child maltreatment. The 845 children who were observed from the age of 4 through 12 years were the subjects of this study. Every 2 years information on gastrointestinal symptoms was obtained from parents, and maltreatment allegations were obtained from Child Protective Services (CPS). At the age of 12 years children reported gastrointestinal symptoms, life-time maltreatment, and psychological distress. Data were analyzed by logistic regression.Results: Lifetime CPS allegations of sexual abuse were associated with abdominal pain at age 12 years (odds ratio [OR] = 1.75; 95% confidence interval [CI] = 1.1-2.47). Sexual abuse preceded or coincided with abdominal pain in 91% of cases. Youth recall of ever having been psychologically, physically, or sexually abused was significantly associated with both abdominal pain and nausea/vomit- ing (range, OR = 1.5 [95% CI, 1.1-2.0] to 2.1 [95% CI, 1.5-2.9]). When adjusting for psychological distress, most effects became insignificant except for the rela- tion between physical abuse and nausea/vomiting (OR = 1.5; 95% CI, 1.1-2.2). Conclusion: Youth who have been maltreated are at increased risk for unex- plained gastrointestinal symptoms, and this relation is partially mediated by psychological distress. These findings are relevant to the clinical care for children who complain of unexplained gastrointestinal symptoms.en_US
dc.description.urihttps://doi.org/10.1370/afm.1053en_US
dc.language.isoen_USen_US
dc.publisherAnnals of Family Medicine, Incen_US
dc.relation.ispartofAnnals of Family Medicine
dc.titleUnexplained gastrointestinal symptoms after abuse in a prospective study of children at risk for abuse and neglecten_US
dc.typeArticleen_US
dc.identifier.doi10.1370/afm.1053
dc.identifier.pmid20212300
dc.identifier.ispublishedYes
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