• Acute glomerulonephritis in a hematopoietic blood stem cell donor

      Chandra, Preeti; Dahiya, Saurabh; Sanchez-Petitto, Gabriela; Malik, Jawad; Bolanos, Jonathan; Haririan, Abdolreza; Weir, Matthew; Drachenberg, Cinthia; Rapoport, Aaron (Dustri-Verlag, 2021-07-01)
      Use of granulocyte colony-stimulating factor (G-CSF) has been associated with side effects including reports of acute glomerulonephritis (GN), almost all of which have been immune complex associated. There is one prior report of pauci-immune GN in a child, but was negative for ANCA (anti-neutrophilic cytoplasmic antibodies). We describe the first case of ANCA-positive pauci-immune GN exacerbated by the use of G-CSF for peripheral blood stem cell (PBSC) donation in a patient with no prior history of vasculitis. Given the use of G-CSF in PBSC donation and neutropenias associated with various conditions, it is important that both the nephrologist and the hematologist are aware of the renal risks associated with its use.
    • Chimeric antigen receptor T-cell therapy after allogeneic stem cell transplant for relapsed/refractory large B-cell lymphoma

      Lutfi, Forat; Holtzman, Noa; Siglin, Jonathan; Bukhari, Ali; Mustafa Ali, Moaath; Kim, Dong; Sanchez-Petitto, Gabriela; Gottlieb, David; Ruehle, Kathleen; Hutnick, Elizabeth; et al. (Blackwell Publishing, 2020-11-10)