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    Cocaine as a rare cause of locked-in syndrome: a case report

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    Author
    Ali, O.
    Bueno, M.G.
    Verceles, A.C.
    Date
    2019
    Journal
    Journal of medical case reports
    Publisher
    BioMed Central Ltd.
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1186/s13256-019-2278-2
    Abstract
    INTRODUCTION: In the United States, cocaine is a commonly used drug of abuse. It is also a recognized contributing factor for both hemorrhagic and ischemic strokes. However, cocaine-induced basilar artery thrombosis has rarely been reported in the literature. CASE PRESENTATION: Our patient was a 51-year-old African American woman with a history of polysubstance abuse who presented to the emergency department for acute behavior changes. Later, during admission, she had a dramatic decrease in motor strength in all extremities and a positive Babinski reflex bilaterally. The results of her toxicology reports were positive for cocaine; in addition, results of magnetic resonance angiography and magnetic resonance imaging were consistent with acute thrombosis and subsequent infarction of the basilar artery. Her mental status improved, but she was only able to communicate via movements of her eyes. CONCLUSION: Our patient developed locked-in syndrome after use of cocaine. Given the prevalence of its use in the United States, cocaine use should be included among the potential causes of locked-in syndrome.
    Keyword
    Basilar artery
    Cocaine-related disorders
    Locked-in syndrome
    Magnetic resonance imaging
    Quadriplegia
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85075115077&doi=10.1186%2fs13256-019-2278-2&partnerID=40&md5=f184a7f36580452068eea1e4b033bd5e; http://hdl.handle.net/10713/11466
    ae974a485f413a2113503eed53cd6c53
    10.1186/s13256-019-2278-2
    Scopus Count
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    UMB Open Access Articles 2019

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