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dc.contributor.authorKhan, M.M.
dc.contributor.authorOyler, B.L.
dc.contributor.authorGoodlett, D.R.
dc.date.accessioned2019-11-20T15:51:42Z
dc.date.available2019-11-20T15:51:42Z
dc.date.issued2019
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85074564849&doi=10.3389%2ffimmu.2019.02388&partnerID=40&md5=60cb9f7ec741664a21e69e7280c9a91b
dc.identifier.urihttp://hdl.handle.net/10713/11430
dc.description.abstractIn recent years, a lot of scientific interest has focused on cancer immunotherapy. Although chronic inflammation has been described as one of the hallmarks of cancer, acute inflammation can actually trigger the immune system to fight diseases, including cancer. Toll-like receptor (TLR) ligands have long been used as adjuvants for traditional vaccines and it seems they may also play a role enhancing efficiency of tumor immunotherapy. The aim of this perspective is to discuss the effects of TLR stimulation in cancer, expression of various TLRs in different types of tumors, and finally the role of TLRs in anti-cancer immunity and tumor rejection. Copyright 2019 The Authors.en_US
dc.description.sponsorshipThis work was supported in part by the Intramural Research Program of NIAID, NIH, National Institutes of Health 1R01AI123820-01 (DG), and the International Centre for Cancer Vaccine Science project of the International Research Agendas program of the Foundation for Polish Science co-financed by the European Union under the European Regional Development Fund (MAB/2017/03) at the University of Gdansk (ZU-W, NM-T, RF, DG, and TH).en_US
dc.description.urihttps://doi.org/10.3389/fimmu.2019.02388en_US
dc.language.isoen_USen_US
dc.publisherFrontiers Media S.A.en_US
dc.relation.ispartofFrontiers in Immunology
dc.subjectAnti-cancer immunityen_US
dc.subjectImmuno-oncologyen_US
dc.subjectImmunotherapyen_US
dc.subjectToll-like receptorsen_US
dc.subjectTumor rejectionen_US
dc.titleThe role of tlrs in anti-cancer immunity and tumor rejectionen_US
dc.typeArticleen_US
dc.identifier.doi10.3389/fimmu.2019.02388
dc.identifier.pmid31695691


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