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dc.contributor.authorBradford, L.L.
dc.contributor.authorChibucos, M.C.
dc.contributor.authorMa, B.
dc.date.accessioned2019-11-01T12:49:33Z
dc.date.available2019-11-01T12:49:33Z
dc.date.issued2017
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85028626279&doi=10.1093%2ffemspd%2fftx061&partnerID=40&md5=15e661cc960b2b826773391c93c22254
dc.identifier.urihttp://hdl.handle.net/10713/11266
dc.description.abstractCandida albicans is the predominant cause of vulvovaginal candidiasis (VVC). Little is known regarding the genetic diversity of Candida spp. in the vagina or the microvariations in strains over time that may contribute to the development of VVC. This study reports the draft genome sequences of four C. albicans and one C. glabrata strains isolated from women with VVC. An SNP-based whole-genome phylogeny indicates that these isolates are closely related; however, phylogenetic distances between them suggest that there may be genetic adaptations driven by unique host environments. These sequences will facilitate further comparative analyses and ultimately improve our understanding of genetic variation in isolates of Candida spp. that are associated with VVC.en_US
dc.description.sponsorshipResearch reported in this publication was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number F31AI116023 and UH2AI083264.en_US
dc.description.urihttps://doi.org/10.1093/femspd/ftx061en_US
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.ispartofPathogens and Disease
dc.subjectCandida albicansen_US
dc.subjectCandida glabrataen_US
dc.subjectClinical isolatesen_US
dc.subjectSingle nucleotide polymorphisms (SNP)en_US
dc.subjectYeast infectionen_US
dc.titleVaginal Candida spp. genomes from women with vulvovaginal candidiasisen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/femspd/ftx061
dc.identifier.pmid28582496


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