• Login
    View Item 
    •   UMB Digital Archive
    • UMB Open Access Articles
    • UMB Open Access Articles 2017
    • View Item
    •   UMB Digital Archive
    • UMB Open Access Articles
    • UMB Open Access Articles 2017
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of UMB Digital ArchiveCommunitiesPublication DateAuthorsTitlesSubjectsThis CollectionPublication DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    Display statistics

    Developing and evaluating a flexible wireless microcoil array based integrated interface for epidural cortical stimulation

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Author
    Wang, X.
    Chaudhry, S.A.
    Hou, W.
    Date
    2017
    Journal
    International Journal of Molecular Sciences
    Publisher
    MDPI AG
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.3390/ijms18020335
    Abstract
    Stroke leads to serious long-term disability. Electrical epidural cortical stimulation has made significant improvements in stroke rehabilitation therapy. We developed a preliminary wireless implantable passive interface, which consists of a stimulating surface electrode, receiving coil, and single flexible passive demodulated circuit printed by flexible printed circuit (FPC) technique and output pulse voltage stimulus by inductively coupling an external circuit. The wireless implantable board was implanted in cats' unilateral epidural space for electrical stimulation of the primary visual cortex (V1) while the evoked responses were recorded on the contralateral V1 using a needle electrode. The wireless implantable board output stable monophasic voltage stimuli. The amplitude of the monophasic voltage output could be adjusted by controlling the voltage of the transmitter circuit within a range of 5-20 V. In acute experiment, cortico-cortical evoked potential (CCEP) response was recorded on the contralateral V1. The amplitude of N2 in CCEP was modulated by adjusting the stimulation intensity of the wireless interface. These results demonstrated that a wireless interface based on a microcoil array can offer a valuable tool for researchers to explore electrical stimulation in research and the dura mater-electrode interface can effectively transmit electrical stimulation. Copyright 2017 by the authors.
    Sponsors
    The work was supported by Natural Science Foundation of Chongqing in China (CSTC2013JCYJA0763) and by R01HL118084 from NIH (to Xiaofeng Jia), and Maryland Stem Cell Research Fund (2013-MSCRFE-146-00) (to Xiaofeng Jia).
    Keyword
    Epidural cortical stimulation
    Inductive coupling
    Micro coil
    Nerve-electrode interface
    Rehabilitation
    Stroke
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85012008461&doi=10.3390%2fijms18020335&partnerID=40&md5=4c6ef5ca09153117353c876f5910cac5; http://hdl.handle.net/10713/11259
    ae974a485f413a2113503eed53cd6c53
    10.3390/ijms18020335
    Scopus Count
    Collections
    UMB Open Access Articles 2017

    entitlement

    Related articles

    • An in-vivo paradigm for the evaluation of stimulating electrodes for use with a visual prosthesis.
    • Authors: Chowdhury V, Morley JW, Coroneo MT
    • Issue date: 2004 May
    • Electrical stimulation with a penetrating optic nerve electrode array elicits visuotopic cortical responses in cats.
    • Authors: Lu Y, Yan Y, Chai X, Ren Q, Chen Y, Li L
    • Issue date: 2013 Jun
    • Recording human electrocorticographic (ECoG) signals for neuroscientific research and real-time functional cortical mapping.
    • Authors: Hill NJ, Gupta D, Brunner P, Gunduz A, Adamo MA, Ritaccio A, Schalk G
    • Issue date: 2012 Jun 26
    • Cortical activation via an implanted wireless retinal prosthesis.
    • Authors: Walter P, Kisvárday ZF, Görtz M, Alteheld N, Rossler G, Stieglitz T, Eysel UT
    • Issue date: 2005 May
    • Surface stimulation of the brain with a prototype array for a visual cortex prosthesis.
    • Authors: Chowdhury V, Morley JW, Coroneo MT
    • Issue date: 2004 Sep
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Policies | Contact Us | UMB Health Sciences & Human Services Library
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.