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    Changes in microbiome during and after travellers' diarrhea: what we know and what we do not

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    Author
    Rasko, D.A.
    Date
    2017
    Journal
    Journal of travel medicine
    Type
    Article
    
    Metadata
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    See at
    https://doi.org/10.1093/jtm/tax017
    Abstract
    The study of bacterial pathogens has advanced from culture on plates to basic biochemical studies; to sequencing reference genomes and attempting to ascribe those qualities to the whole species; to evaluating complete communities based on the universal marker of the 16S rRNA gene; to now sequencing all available nucleic acids in any sample to characterize the community as a whole. These types of scientific advances highlight that there are multiple layers of information within any sample, and to some extent we are only now beginning to be able to identify, categorize and understand the complex interactions of the host, pathogen and microbiome. In most cases, we can only now generate the data to examine these samples, but the detailed understanding of the significance of the data is lacking. We anticipate that in the future these microbiota and community data will be able to be modelled, understood and potentially used as either markers of disease, or diagnostics. This review provides a brief overview of the state of the use of microbiome studies using Travellers Diarrhea samples and what those studies have told us. More importantly these studies highlight what is remaining to be elucidated.
    Keyword
    microbiome
    Travelers' diarrhea
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042659256&doi=10.1093%2fjtm%2ftax017&partnerID=40&md5=ae2656d132cdfe455fdf8de44d60d724; http://hdl.handle.net/10713/10928
    ae974a485f413a2113503eed53cd6c53
    10.1093/jtm/tax017
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    UMB Open Access Articles 2017

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