Effects of Fluoride and Calcium Phosphate Materials on Remineralization of Mild and Severe White Spot Lesions
JournalBioMed Research International
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AbstractFixed orthodontic treatments often lead to enamel demineralization and cause white spot lesions (WSLs). The aim of this study was to evaluate the mineralization degree of 2 types of WSLs based on ICDAS index and compare the remineralizing efficacy of 3 oral hygiene practices after 1 month and 3 months. 80 mild demineralized and 80 severe demineralized enamel specimens were randomized into three treatments: fluoride toothpaste (FT), fluoride varnish plus fluoride toothpaste (FV+FT), and CPP-ACP plus fluoride toothpaste (CPP-ACP+FT). Microhardness tester, DIAGNODent Pen 2190, and scanning electron microscope were used to evaluate the changes of mineralization degree. Both qualitative and quantitative indicators suggested that the mild and severe white spot lesions were different in the degree of mineralization. Severe WSLs demineralized much more seriously than mild lesions even after 3 months of treatment. Despite the variation in severity, both lesions had the same variation trend after each measure was applied: FT had weak therapeutic effect, FV + FT and CPP-ACP + FT were effective for remineralization. Their remineralizing efficacy was similar after 1 month, and combined use of CPP-ACP plus F toothpaste was more effective after 3 months. In order to fight WSLs, early diagnosis was of great importance, and examination of the tooth surface after air-dry for 5 seconds was recommended. Also, when WSLs were found, added remineralizing treatments were required. Copyright 2019 Zixiang Dai et al.
SponsorsThis study was supported by the National Natural Science Foundation of China grant 81400540 (Ke Zhang), Beijing Municipal Administration of Hospitals' Youth Program QML20151401 (Ke Zhang), Beijing Municipal Administration of Hospital Clinical Medicine Development of Special Funding Support ZYLX201703 (Yuxing Bai), and Beijing Municipal Administration of Hospitals' Ascent Plan DFL20151401 (Yuxing Bai).
Identifier to cite or link to this itemhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85068623029&doi=10.1155%2f2019%2f1271523&partnerID=40&md5=c963571d8ff43276e72bae6c575546e0; http://hdl.handle.net/10713/10616