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    Novel protein-repellent and antibacterial resins and cements to inhibit lesions and protect teeth

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    Author
    Wu, J.
    Baras, B.
    Bhadila, G.
    Li, Y.
    Melo, M.A.S.
    Xu, H.H.K.
    Zhang, N.
    Weir, M.D.
    Date
    2019
    Journal
    International Journal of Polymer Science
    Publisher
    Hindawi Limited
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1155/2019/5602904
    Abstract
    Orthodontic treatment is increasingly popular as people worldwide seek esthetics and better quality of life. In orthodontic treatment, complex appliances and retainers are placed in the patients’ mouths for at least one year, which often lead to biofilm plaque accumulation. This in turn increases the caries-inducing bacteria, decreases the pH of the retained plaque on an enamel surface, and causes white spot lesions (WSLs) in enamel. This article reviews the cutting-edge research on a new class of bioactive and therapeutic dental resins, cements, and adhesives that can inhibit biofilms and protect tooth structures. The novel approaches include the use of protein-repellent and anticaries polymeric dental cements containing 2-methacryloyloxyethyl phosphorylcholine (MPC) and dimethylaminododecyl methacrylate (DMAHDM)
    multifunctional resins that can inhibit enamel demineralization
    protein-repellent and self-etching adhesives to greatly reduce oral biofilm growth
    and novel polymethyl methacrylate resins to suppress oral biofilms and acid production. These new materials could reduce biofilm attachment, raise local biofilm pH, and facilitate the remineralization to protect the teeth. This novel class of dental resin with dual benefits of antibacterial and protein-repellent capabilities has the potential for a wide range of dental and biomedical applications to inhibit bacterial infection and protect the tissues. Copyright 2019 Li Cao et al.
    Sponsors
    This study was supported by Beijing Hospitals Program (ZYLX201703) (YB)
    National Key R&D Program of China (2017YFC1104304) (YB)
    National Natural Science Foundation (NSF) of China (81671032) (JLW)
    University of Maryland, Baltimore County seed grant (HX)
    and School of Dentistry, University of Maryland bridge fund (HX).
    Keyword
    Anti-Bacterial Agents
    Biofilms
    Dental Cements
    Orthodontics
    Resins, Synthetic
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071234030&doi=10.1155%2f2019%2f5602904&partnerID=40&md5=02758f20698177bcef67215aaafb5772; http://hdl.handle.net/10713/10506
    ae974a485f413a2113503eed53cd6c53
    10.1155/2019/5602904
    Scopus Count
    Collections
    UMB Open Access Articles 2019

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