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dc.contributor.authorByrd, A.S.
dc.contributor.authorDina, Y.
dc.contributor.authorQuartey, Q.Q.
dc.date.accessioned2019-09-10T17:30:14Z
dc.date.available2019-09-10T17:30:14Z
dc.date.issued2019
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85071092290&doi=10.1038%2fs41598-019-48226-w&partnerID=40&md5=52330200a2bd2e91f25b53491605c1b1
dc.identifier.urihttp://hdl.handle.net/10713/10487
dc.description.abstractHidradenitis suppurativa (HS) is a chronic inflammatory disorder characterized by painful nodules, sinus tracts, and scars occurring predominantly in intertriginous regions. The prevalence of HS is currently 0.053–4%, with a predominance in African-American women and has been linked to low socioeconomic status. The majority of the reported literature is retrospective, population based, epidemiologic studies. In this regard, there is a need to establish a repository of biospecimens, which represent appropriate gender and racial demographics amongst HS patients. These efforts will diminish knowledge gaps in understanding the disease pathophysiology. Hence, we sought to outline a step-by-step protocol detailing how we established our HS biobank to facilitate the formation of other HS tissue banks. Equipping researchers with carefully detailed processes for collection of HS specimens would accelerate the accumulation of well-organized human biological material. Over time, the scientific community will have access to a broad range of HS tissue biospecimens, ultimately leading to more rigorous basic and translational research. Moreover, an improved understanding of the pathophysiology is necessary for the discovery of novel therapies for this debilitating disease. We aim to provide high impact translational research methodology for cutaneous biology research and foster multidisciplinary collaboration and advancement of our understanding of cutaneous diseases. Copyright 2019, The Author(s).en_US
dc.description.urihttps://doi.org/10.1038/s41598-019-48226-wen_US
dc.language.isoen-USen_US
dc.publisherNature Publishing Groupen_US
dc.relation.ispartofScientific Reports
dc.subject.meshHidradenitis Suppurativaen_US
dc.subject.meshBiological Specimen Banks--organization & administrationen_US
dc.titleSpecimen Collection for Translational Studies in Hidradenitis Suppurativaen_US
dc.typeArticleen_US
dc.identifier.doi10.1038/s41598-019-48226-w
dc.identifier.pmid31434914


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