Specimen Collection for Translational Studies in Hidradenitis Suppurativa
PublisherNature Publishing Group
MetadataShow full item record
AbstractHidradenitis suppurativa (HS) is a chronic inflammatory disorder characterized by painful nodules, sinus tracts, and scars occurring predominantly in intertriginous regions. The prevalence of HS is currently 0.053–4%, with a predominance in African-American women and has been linked to low socioeconomic status. The majority of the reported literature is retrospective, population based, epidemiologic studies. In this regard, there is a need to establish a repository of biospecimens, which represent appropriate gender and racial demographics amongst HS patients. These efforts will diminish knowledge gaps in understanding the disease pathophysiology. Hence, we sought to outline a step-by-step protocol detailing how we established our HS biobank to facilitate the formation of other HS tissue banks. Equipping researchers with carefully detailed processes for collection of HS specimens would accelerate the accumulation of well-organized human biological material. Over time, the scientific community will have access to a broad range of HS tissue biospecimens, ultimately leading to more rigorous basic and translational research. Moreover, an improved understanding of the pathophysiology is necessary for the discovery of novel therapies for this debilitating disease. We aim to provide high impact translational research methodology for cutaneous biology research and foster multidisciplinary collaboration and advancement of our understanding of cutaneous diseases. Copyright 2019, The Author(s).
Identifier to cite or link to this itemhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85071092290&doi=10.1038%2fs41598-019-48226-w&partnerID=40&md5=52330200a2bd2e91f25b53491605c1b1; http://hdl.handle.net/10713/10487
- Examining the race-specific prevalence of hidradenitis suppurativa at a large academic center; results from a retrospective chart review.
- Authors: Vaidya T, Vangipuram R, Alikhan A
- Issue date: 2017 Jun 15
- Complications of hidradenitis suppurativa.
- Authors: Yuan JT, Naik HB
- Issue date: 2017 Jun
- Understanding the Relationship Between Smoking and Hidradenitis Suppurativa.
- Authors: Bukvić Mokos Z, Miše J, Balić A, Marinović B
- Issue date: 2020 Jul
- Physician perspectives on complementary and alternative medicine in hidradenitis suppurativa.
- Authors: Price KN, Collier EK, Grogan T, Fernandez JM, Alhusayen R, Alavi A, Hamzavi IH, Lowes MA, Porter MJ, Hsiao JL, Shi VY
- Issue date: 2021 Mar
- Hidradenitis suppurativa in the pediatric population.
- Authors: Liy-Wong C, Pope E, Lara-Corrales I
- Issue date: 2015 Nov