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    Specimen Collection for Translational Studies in Hidradenitis Suppurativa

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    Author
    Byrd, A.S.
    Dina, Y.
    Quartey, Q.Q.
    Date
    2019
    Journal
    Scientific Reports
    Publisher
    Nature Publishing Group
    Type
    Article
    
    Metadata
    Show full item record
    See at
    https://doi.org/10.1038/s41598-019-48226-w
    Abstract
    Hidradenitis suppurativa (HS) is a chronic inflammatory disorder characterized by painful nodules, sinus tracts, and scars occurring predominantly in intertriginous regions. The prevalence of HS is currently 0.053–4%, with a predominance in African-American women and has been linked to low socioeconomic status. The majority of the reported literature is retrospective, population based, epidemiologic studies. In this regard, there is a need to establish a repository of biospecimens, which represent appropriate gender and racial demographics amongst HS patients. These efforts will diminish knowledge gaps in understanding the disease pathophysiology. Hence, we sought to outline a step-by-step protocol detailing how we established our HS biobank to facilitate the formation of other HS tissue banks. Equipping researchers with carefully detailed processes for collection of HS specimens would accelerate the accumulation of well-organized human biological material. Over time, the scientific community will have access to a broad range of HS tissue biospecimens, ultimately leading to more rigorous basic and translational research. Moreover, an improved understanding of the pathophysiology is necessary for the discovery of novel therapies for this debilitating disease. We aim to provide high impact translational research methodology for cutaneous biology research and foster multidisciplinary collaboration and advancement of our understanding of cutaneous diseases. Copyright 2019, The Author(s).
    Keyword
    Hidradenitis Suppurativa
    Biological Specimen Banks--organization & administration
    Identifier to cite or link to this item
    https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071092290&doi=10.1038%2fs41598-019-48226-w&partnerID=40&md5=52330200a2bd2e91f25b53491605c1b1; http://hdl.handle.net/10713/10487
    ae974a485f413a2113503eed53cd6c53
    10.1038/s41598-019-48226-w
    Scopus Count
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    UMB Open Access Articles 2019

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