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dc.contributor.authorOrtiz, Justin R.
dc.contributor.authorNeuzil, Kathleen M.
dc.creatorOrtiz, J.
dc.date.accessioned2019-08-12T13:29:30Z
dc.date.available2019-08-12T13:29:30Z
dc.date.issued2019-04-08
dc.identifier.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85064507180&origin=inward
dc.identifier.urihttp://hdl.handle.net/10713/10310
dc.description.abstractInfluenza vaccines have a long history of safety and demonstrated efficacy; however, they are seldom used in low- and middle-income countries (LMICs). Although reasons for underuse are multifactorial and differ from country to country, the need for up to twice-annual reformulation and yearly vaccination are obstacles to influenza prevention in LMICs. Major efforts are underway to produce next-generation influenza vaccines that provide durable protection against drifted strains, and such vaccines could address these unmet needs. However, additional information is required to influence immunization policies in most LMICs. Better estimates of vaccine impact on important public health outcomes, more affordable vaccines, improved programmatic suitability, and strengthened immunization delivery infrastructures are needed and must be considered early during the development of new vaccines if widespread adoption in LMICs is to be achieved. © The Author(s) 2019.en_US
dc.description.urihttps://doi.org/10.1093/infdis/jiz024en_US
dc.language.isoen_USen_US
dc.publisherOxford University Press.en_US
dc.relation.ispartofThe Journal of infectious diseasesen_US
dc.subjectglobal healthen_US
dc.subjectinfluenza vaccineen_US
dc.subjectvaccine developmenten_US
dc.titleInfluenza Immunization in Low- and Middle-Income Countries: Preparing for Next-Generation Influenza Vaccinesen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/infdis/jiz024
dc.identifier.pmid30715348
dc.relation.volume219


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