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dc.contributor.authorHe, T.
dc.contributor.authorLardieri, A.B.
dc.contributor.authorMorgan, J.A.
dc.date.accessioned2019-08-02T17:28:31Z
dc.date.available2019-08-02T17:28:31Z
dc.date.issued2018
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85056573425&doi=10.5863%2f1551-6776-23.4.293&partnerID=40&md5=5d5b2fbfdbb1f6475da128828fcff3bf
dc.identifier.urihttp://hdl.handle.net/10713/10152
dc.description.abstractOBJECTIVES In 2011, approximately 1.7 million pediatric patients had a codeine-containing prescription filled at a US retail pharmacy. Numerous cases involving serious adverse effects or fatalities have been reported in children who have been prescribed codeine. In 2013, the US Food and Drug Administration added a boxed warning to avoid codeine in children after a tonsillectomy. The purpose of this study is to determine pharmacists' and pediatricians' knowledge of the boxed warning for codeine in children. METHODS Two separate surveys were administered to community pharmacists in Maryland, pediatricians, and pediatric residents at a single institution in Maryland. Both surveys consisted of questions regarding knowledge of the boxed warning for codeine in children. RESULTS There was no difference in the awareness of the boxed warning between pharmacists (48.9%, n = 43) and pediatricians (51.3%, n = 41, p = 0.88). More pharmacists knew that ultrarapid metabolizers have the risk for increased adverse events from codeine (39.5% pharmacists vs. 20% pediatricians, p = 0.01). In addition, 36% of pharmacists and 33% of pediatricians noted that it was never appropriate to use codeine in a child (p = 0.73). CONCLUSIONS Only half of pharmacists and pediatricians surveyed were aware of the boxed warning for codeine. One third of pharmacists and pediatricians in this study would never use codeine in a child. Therefore, more education is needed for pharmacists and pediatricians regarding the dangers of using codeine in children. Copyright Published by the Pediatric Pharmacy Advocacy Group. All rights reserved.en_US
dc.description.urihttps://dx.doi.org/10.5863/1551-6776-23.4.293en_US
dc.description.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117814/en_US
dc.language.isoEnglishen_US
dc.publisherPediatric Pharmacy Advocacy Group, Inc.en_US
dc.relation.ispartofJournal of Pediatric Pharmacology and Therapeutics
dc.subjectAdverse drug effecten_US
dc.subjectBoxed warningen_US
dc.subjectChildrenen_US
dc.subjectCodeineen_US
dc.subjectPediatricen_US
dc.titlePharmacist and pediatrician knowledge of codeine use in childrenen_US
dc.typeArticleen_US
dc.identifier.doi10.5863/1551-6776-23.4.293


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