The 2017-2021 University of Maryland, Baltimore (UMB) Strategic Plan emphasizes that UMB will achieve its goal of becoming a dominant economic leader in the region through innovation and entrepreneurship. The plan seeks to harness UMB’s strengths in interdisciplinary and interprofessional teamwork to serve as a catalyst for economic development. This plan incorporates initiatives from all of UMB’s seven schools: the Graduate School and the schools of dentistry, law, medicine, nursing, pharmacy, and social work. Therefore, the 2016-2017 President’s Fellows, an interdisciplinary group of UMB students, were tasked with writing this white paper to assess the current state of entrepreneurship at UMB, to identify existing gaps, and to make appropriate recommendations.