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Effects of Glycemic Control on Dental Implant Stabilization for Patients with Type 2 Diabetes

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Slevin, Terry
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2017
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dissertation
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This study evaluated the effects of hyperglycemia on dental implant integration using resonance frequency analysis in 161 patients over a four-month period following placement of two mandibular implants. HbA1c levels were determined at the time of surgery, two and four months following placement. Stability was normalized relative to the change from baseline. Implant stability was analyzed for associations relative to HbA1c categories (<6%, 6.0-7.9%, 8.0-9.9%, 10.0-12.0%). Statistically significant differences were noted with respect to change in RFA relative to HbA1c and time with the poorly controlled group showing the greatest mean decrease in stability (p<0.001). The calculated time for implants to return to baseline levels of stability increased in direct proportion to increasing hyperglycemia, with the poorly controlled group taking twice as long to return to baseline as the control group. This study demonstrates important compromises in implant stabilization in type 2 diabetic patients in direct relation to increasing HbA1c levels consistent with alterations in bone healing for patients with worsening glycemic control.

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University of Maryland, Baltimore. Biomedical Sciences-Dental School. M.S. 2017
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