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“Independent” reanalysis of landmark starch solutions trial was published by original authors
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Doshi, Peter
Doshi, Peter
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2017-07-21
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BMJ Publishing Group
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Is a reanalysis of clinical trial data truly independent if 6 of the 8 authors are associated with the organization that administered the original study? Moreover, 3 of the 6 are among the authors of the initial article, one of whom was the principal investigator. Peter Doshi discusses the Crystalloid versus Hydroxyethyl Starch Trial (CHEST), lack of data transparency, and concerns over the validity of the reanalysis
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Doshi, P. (2017). "Independent" reanalysis of landmark starch solutions trial was published by original authors. BMJ, 358:j3552. DOI: 10.1136/bmj.j3552