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Item Innovative Approach to Graduate Capstone Project Development(2024-06-01) Mishler, Oksana; Bress, Lisa; Burgee, SuzanneItem A PHENOMENOLOGICAL STUDY OF PREDOCTORAL DENTAL STUDENTS’ EXPERIENCES WITH SERVICE-LEARNING(2024-04-12) Schneider, Monica, D.D.S., M.S.; Kulo, VioletThe purpose of this qualitative phenomenological study is to understand predoctoral dental students’ lived experiences with service-learning (SL) in general dentistry and explore how these experiences influence their perceptions of community service and future professional practice. Purposive sampling will be used to identify predoctoral students from dental schools with SL rotations that satisfy the study criteria. A SL rotation in this study is defined as an experiential learning approach that aims to encourage civic awareness and participation. The sample for this study is senior predoctoral dental students enrolled in an accredited dental school program in the United States that participate in a SL clinical rotation during their dental education training. Data will be collected by performing virtual semi-structured interviews. Data analysis includes an iterative process and inductive approach where a thematic framework is developed to create an initial list of codes and analyze data to develop themes and descriptions of the participants’ experiences and report the essence of the phenomenon. SL experiences in dental schools vary in their organization, structure, type of assessments used, length of the experience, and type of learning site. It is not clear whether students get comparable SL experiences that might impact their perspectives on community service and future professional practice. In addition, this study will expand the understanding of Mezirow’s (2000) transformative learning theory and add to the base of the theoretical literature. Particularly, dental students SL clinical experiences might present a disorienting dilemma which is connected to the initiation of the transformative learning process.Item Role of Gut Microbiota in Osteoclast Regulation and Skeletal Homeostasis(2024-01-16) Tanwar, Himanshi; Gnanasekaran, Jeba Mercy; Allison, Devon Lea; Thumbigere-Math, VivekItem Factors affecting tooth loss among diabetic patients at an academic institution(2024-03-06) Zimmerman, Erica; Oh, Se-Lim; Chen, HegangItem Influence of Imidazolium-Based Ionic Liquids on Acrylic Denture Base Materials(2024-03-13) Garcia, Isadora Martini; Virgina, Serra de Souza; Scholten, Jackson Damiani; Mezzomo Collares, Fabrício; Sampaio De Melo, Mary AnneItem Effects of Environmental Enrichment on Visceral Sensitivity and Brain Connectivity in a Mouse Model of Chronic Overlapping Pain Conditions(2023-11-11) MIchael, Keaser; Hanson, Shelby; Scott, Alison June; Traub, Richard J.; Da Silva, Joyce T.Item Sex differences in diffuse noxious inhibitory control (DNIC) are mediated by the rostral anterior cingulate cortex (rACC) periaqueductal gray (PAG) circuit(2023-10-25) Rocha, Igor Rafael Correia; Santo, Renan; Zhang, Youping; Da Silva, Joyce T.; Ro, Jin Y.Item Metformin and other metabolic inhibitors attenuate neuropathic pain and tumor growth in mice with paraneoplastic syndrome and CIPN(2023-11-15) Kuppusamy, Panjamurthy; Haque, Mamunui; Melemedijian, OhannesChemotherapy-induced peripheral neuropathy (CIPN) and paraneoplastic neurological syndrome are two conditions that can cause significant pain and discomfort in cancer patients. CIPN is a common side effect of certain chemotherapeutics and can result in numbness, tingling, and pain. Paraneoplastic neurological syndrome, on the other hand, is a rare disorder that occurs when cancer-fighting antibodies attack parts of the nervous system. Both neuropathies can persist which can adversely affect the quality of life and the rehabilitation of cancer patients. Unfortunately, therapies that can alleviate tumor or chemotherapy-induced neuropathic pain that do not interfere with tumor growth do not currently exist. The main goal of this study was to identify a therapeutic strategy that can achieve both anti-tumor and analgesic effects. The chemotherapeutic, bortezomib, has been shown to induce aerobic glycolysis in sensory neurons which lead to bortezomib-induce neuropathic pain. Aerobic glycolysis is also a hallmark of cancer cells, suggesting a common metabolic vulnerability. Paraneoplastic neuropathies are commonly associated with lung cancers. Hence, we used Lewis Lung Carcinoma cells (LLC1) to develop a mouse model of paraneoplastic neuropathy. We hypothesized that blocking metabolic pathways could alleviate CIPN and paraneoplastic neuropathic pain without compromising on tumor control. To test our hypothesis, we demonstrated that mice implanted with LLC1 developed significant allodynia. Treatment with bortezomib attenuated tumor growth but exacerbated the neuropathic pain. However, co-treatment with metformin, which blocks bortezomib- induced aerobic glycolysis in sensory neurons and prevents CIPN, attenuated both tumor growth and neuropathic pain. Similarly, inhibition of lactate dehydrogenase and pyruvate dehydrogenase kinase with oxamate and dichloroacetate respectively, also reduced tumor growth and pain. These results suggest that targeting metabolic pathways is a promising strategy to improve oncologic outcomes and alleviate neuropathic pain in cancer patients.Item Addressing Barriers to Dental Care Access for Undocumented Pregnant Moms(2023-06-09) Young, Mariela; Harasta, Qian; Dedgeba, HikamItem 2023 USA Brain Bee Championship(2023-06-26) Manuella, Yassa; Myslinski, NorbertItem The Interconnection Between Periodontitis and Inflammatory Bowel Disease(2023-05-12) Tanwar, Himanshi; Das, Amitabh; Yesupatham, Sathish; Dilshad, Yasir; Kear, Bernice; Chung, Man-Kyo; Rasko, David A.; Ernst, Robert K.; Raufman, Jean-Pierre; Thumbigere-Math, Vivek; Gnanasekaran, Jeba Mercy; Allison, Devon LeaItem Three-Dimensional Assessment of Virtual Clear Aligner Attachment Removal: A Prospective Clinical Study(2023-04-22) Dock, Jeremy; Shirmohammadi, Iman; Bosio, Jose A.; Copello, FlavioItem Silencing of nociceptive afferents attenuates hyperalgesia but not condylar degeneration of TMJ after injury.(2023-03-31) Alshanqiti, Ishraq; Kumari, Sinu; Hu, Sophia; Chung, Man-KyoItem Novel Calcium Phosphate and Calcium Fluoride Nanocomposites with Antibacterial and Low Shrinkage Stress Capabilities to Inhibit Dental Caries(2023) Alhussein, Abdullah; Alsahafi, Rashed; Balhaddad, AbdulRahman A.; Hack, Gary, D.D.S.; Oates, Thomas W.; Sun, Jirun; Weir, Michael D.; Xu, Hockin H. K.Item The Diamond Scholars Program: Accelerating Clinical Education for Pre-Doctoral Students(2023-03-10) Eisner, Adam; Alkhubaizi, Qoot; Barnes, Douglas; D’Affronte, LisaItem Assessing Postpartum Oral Health Literacy and Needs as Medicaid Dental Coverage Expands(2022-07) Christensen, Paige; Kim, Hee Yeon; Yates, Kristin; Bress, LisaItem A non-classical mechanism of β-lactam resistance in Methicillin Resistant Staphylococcus aureus (MRSA) and its effect on virulence(2022-06) Satishkumar, Nidhi; Lai, Li-Yin; Poon, Raymond; Mukkayyan, Nagaraja; Chatterjee, Som S.Item Synergistic action of GdpP and PBP4 mediates high-level, broad-spectrum, non-classical β-lactam Resistance in Staphylococcus aureus(2022-06) Lai, Li-Yin; Satishkumar, Nidhi; Poon, Raymond; Mukkayyan, Nagaraja; Chatterjee, Som S.Item Human Resources Management and Best Practices for the Department Administrator(2022) Hoffman, William F., Jr.; Levin, Elenora
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