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Title: “Independent” reanalysis of landmark starch solutions trial was published by original authors
Doshi_BMJ_Independent_Reanalysis.pdf  (929.54 kB)  
External Resource/s: Click here for the free full-text article on publisher’s website
Authors: Doshi, Peter
Date: 2017-07-21
Publisher: BMJ Publishing Group
Citation: Doshi, P. (2017). "Independent" reanalysis of landmark starch solutions trial was published by original authors. BMJ, 358:j3552. DOI: 10.1136/bmj.j3552
Subject Keywords: data sharing
independent reanalysis
research transparency
George Institute for Global Health
Duke Clinical Research Institute
Fresenius Kabi
Access to Information
Clinical Trials as Topic
Hydroxyethyl Starch Derivatives
Description: Is a reanalysis of clinical trial data truly independent if 6 of the 8 authors are associated with the organization that administered the original study? Moreover, 3 of the 6 are among the authors of the initial article, one of whom was the principal investigator. Peter Doshi discusses the Crystalloid versus Hydroxyethyl Starch Trial (CHEST), lack of data transparency, and concerns over the validity of the reanalysis.
Type: Article
Appears in Collections:Dr. Peter Doshi

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